Blueprints

Question 1

CA-125

Answer 1

Ovarian cancer tumor marker
-but not that specific: also elevated in many other gyn cancers (fallopian tube, endometrial) and nongynecologic (pancreatic, lung, breast, colon)

Question 2

Tumor marker for ovarian cancer

Answer 2

CA-125

Question 3

Which gynecologic tumor is most likely to present

(a) late stage
(b) early stage

Answer 3

(a) Ovarian cancer presents late- 75% present in stage III/IV disease
(b) Endometrial cancer caught early

Question 4

Taxol

Answer 4

Chemotherapy combo drug: carboplastin + paclitaxel

Question 5

Ideal contraception for F w/ h/o DVT

Answer 5

Need to avoid estrogens b/c of coagulation risk => can use progestin-only options

• Minipills = progestin only pills
• Mirena = progestin-containing IUD

Question 6

Possible option for longer-acting (not daily) contraception for F on warfarin

Answer 6

Depo-provera: q3 mo injection of progesterone only

-causes amenorrhea (decreased or no bleeding) in 50% at one year

Question 7

Ideal contraception option for 36 yo F heavy smoker

Answer 7

Need to avoid estrogens b/c of increased LDL and decreased HDL/coagulation risk => can use progestin-only options

• Minipills = progestin only pills
• Mirena = progestin-containing IUD

Question 8

4 categories of ovarian neoplasm based on origin

Answer 8

1. surface epithelial cells- usually serous
2. germ cell- teratomas
3. sex cord-stroma
4. mets