Blood values Flashcards
Haemoglobin
Normal values: M 130-180g/L; F 115-165g/L
Low: anaemia (microcytic, macrocytic, normocytic), pregnancy, marrow failure
High: polycythaemia
Ca2+
Normal: 2.15-2.65mmol/L
Calcium in term baby
Normal: 2.10-2.95mmol/L
High:
Low:
Calcium in preterm baby
Normal: 1.90-2.85mmol/L
Phosphate
Normal: 0.80-1.40mmol/L
Phosphate in term baby
Normal: 0.95-1.70mmol/L
High:
Low: osteopenia of prematurity
Phosphate in preterm baby
Normal: 0.93-1.72mmol/L
High:
Low: osteopenia of prematurity
TSH
Normal: 0.33-4.5U/L
High: hypothyroidism (Hashimoto’s disease, atrophic thyroid, post RAI or surgery), post-thyroiditis, sick euthyroid
Low: hyperthyroidism (Graves’ disease, toxic multi nodular adenoma, subacute thyroiditis, post partum thyroiditis)
Free T3
Normal: 3.2-6.5pmol/L
High: hyperthyroidism (Graves’ disease, toxic multi nodular adenoma, subacute thyroiditis, post partum thyroiditis)
Low: hypothyroidism (Hashimoto’s disease, atrophic thyroid, post RAI or surgery), post-thyroiditis, sick euthyroid
Free T4
Normal: 10.2-22.0pmol/L
High: hyperthyroidism (Graves’ disease, toxic multi nodular adenoma, subacute thyroiditis, post partum thyroiditis)
Low: hypothyroidism (Hashimoto’s disease, atrophic thyroid, post RAI or surgery), post-thyroiditis, sick euthyroid
Thyroglobulin
<5ug/L
High: pregnancy, papillary or follicular thyroid carcinoma
White cell count
Normal: 3.6-11.0x10^9/L
Platelet count
Normal: 140-400x10^9/L
Neutrophils
Normal: 1.8-7.5x10^9/L
High: bacterial infection, inflammation, myeloproliferation, drugs (steroids), disseminated malignancy, stress (haemorrhage, trauma, surgery, burns, seizure)
Low: viral infections, drugs (chemotherapy, cytotoxic, carbimazole, sulphonamides), sepsis, SLE, haemolytic anaemia, bone marrow failure, hypersplenism
Lymphocytes
Normal: 1.0-4.0x10^9/L
High: acute viral infections, chronic infections, leukaemia, lymphoma
Low: steroids, SLE, uraemia, Legionnaire’s disease, HIV, marrow infiltration, chemotherapy, radiotherapy
Monocytes
Normal: 0.2-0.8x10^9/L
High: chemotherapy, radiotherapy, chronic infection, malignancy, myelodysplasia
Eosinophils
Normal: 0.1-0.4x10^9/L
High: drug reactions (erythema multiforme), allergies, afoot, parasitic infections, skin disease, malignancy
Basophils
Normal: 0.02-0.1x10^9/L
High: myeloproliferation, viral infections, hypersensitivity, inflammatory disorders
Red cell count
Normal: M 4.5-6.5x10^12/L; F 3.8-5.8x10^12/L
Haematocrit
Normal: M 0.4-0.54L/L; F 0.37-0.47L/L
Mean cell volume
Normal: 80-100fL
Low: microcytic anaemia (iron deficiency, thalassaemia, sideroblastic)
High: macrocytic anaemia (B12 deficiency, alcohol, reticulocytosis, drugs eg hydroxycarbamide and phenytoin, hypothyroidism, marrow infiltration, myelodysplasia), haemolytic anaemia (if many young RBCs present)
Mean corpuscular haemoglobin
Normal: 27-32pg/cell
Low: iron-deficiency anaemia
Reticulocyte count
Normal: 0.2-2%
High: haemolysis, haemorrhage, recently treated iron/B12 deficiency anaemia
Prothrombin time
Normal: 10-14s
Activated partial thromboplastin time (APTT)
Normal: 24-37s
Fibrinogen
Normal: 1.5-4.5s
Ferritin
Normal: M 25-350ng/mL; F 10-300ng/mL
Low: iron deficiency
High: anaemia of chronic disease, chronic haemolysis, haemochromatosis, sideroblastic anaemia
Vitamin B12
Normal: 180-1000pg/mL
Folate
Normal: >4.0ng/mL
Na+
Normal: 133-146mmol/L
K+
Normal: 3.5-5.3mmol/L
Mg2+
Normal: 0.7-1.0mmol/L
Urea
Normal: 2.5-7.8mmol/L
Creatinine
Normal: M 59-104umol/L; F 45-84umol/L
Alkaline phosphatase (ALP)
Normal: 30-130U/L
Alanine aminotransferase (ALT)
Normal: M <41U/L; F <33U/L
Bilirubin
Normal: <21umol/L
Gamma-glutimyl transferase (GGT)
Normal: M <60U/L; F <40U/L
Albumin
Normal: 35-50g/L
Creatinine kinase (CK)
Normal: M 40-320U/L; F 25-200U/L
Lactate dehydrogenase (LDH)
Normal: 240-480U/L
Lactate
Normal: 0.5-2.2mmol/L
Urate
Normal: M 200-430umol/L; F 140-360umol/L
Amylase
Normal: 28-100U/dL
Cholesterol
Normal: <5mmol/L
Triglyceride
Normal: 0.55-1.90mmmol/L
LDL
Normal: <3mmol/L
HDL
Normal: >1mmol/L
Cholesterol/HDL
Normal: <4
Erythrocyte sedimentation rate (ESR)
Normal: M <49yo 1-7; M >50yo 2-10; F <49yo 3-9; F >50yo 5-15
C-reactive protein (CRP)
Normal: <5mg/L
GH (random)
Normal: M <5ng/mL; F <10ng/mL
Cortisol (random)
Normal: 137-429nmol/L
Testosterone
Normal: M <49yo 10-45nmol/L; >50yo 6.2-26nmol/L; F <2.0nmol/L
Fasting blood glucose
Normal: 4.0-6.0mmol/L
Postprandial blood glucose (2h after eating)
Normal: <7.8mmol/L
HbA1c
Normal: <42mmol/mol (6.0%)
pH
Normal: 7.35-7.45
ABG: pO2
Normal: 11-13kPa
ABG: pCO2
Normal: 4.7-6.0kPa
HCO3
Normal: 22-26mmol/L
Base excess (BE)
Normal: -2 to +2mmol/L
Red cell distribution width (RCDW)
Normal: 11.5-14.6%
High: mixed macrocytic and microcytic anaemias (eg malabsorption)
Iron
Normal: M 14-32umol/L; F 10-28umol/L
Low: iron deficiency, anaemia of chronic disease
High: chronic haemolysis, haemochromatosis, pregnancy, sideroblastic anaemia
Total iron binding capacity (TIBC)
Normal: 45-72umol/L
Low: chronic haemolysis, haemochromatosis, anaemia of chronic disease
High: iron deficiency, pregnancy
Prothrombin time (PT)
Normal: differs dependent on site, is normalised using INR (normal 0.9-1.2)
High: Faulty extrinsic pathway (e.g. warfarin, vitamin K deficient, liver disease, DIC)
Activated partial thromboplastin time (APTT)
Normal: 35-45s
High: Intrinsic pathway deficiency (e.g. heparin, haemophilia, DIC, liver disease, haemophilia, von Willebrand’s disease)
Thrombin time
Normal: 10-15s
High: heparin, DIC, dysfibrinogenaemia
D-dimers
Normal:
High: DIC, VTE (DVT/PE), inflammation (including infection and malignancy)
Bleeding time
Normal: <10min
High: DIC, liver disease, platelet deficiency, von Willebrand’s disease