Blood transfusions Flashcards
Blood types, antigens, antibodies, universals
Type A (A antigen, B antibody) Type B (B antigen, A antibody) Type AB (A and B antigens, no antibodies) - Universal recipient Type O (No antigens, antibodies to A and B) - Universal donor
Also consider Rh/Factor D
How to make sure blood is safe to give?
Match the blood type. (Testing, cross matching (?))
Disease testing: Nucleic acid technology, Hep C, HIV, West nile virus, syphilis, etc
Types of blood products
Whole blood RBCs Albumin Platelets FFP Cryoprecipitates
whole blood considerations
rarely given because its a lot of volume, and has a lot more things in it for the patient to potentially react to
RBCs
-packed RBC (usually for anemia, ~350 mL)
-washed RBC (for someone who gets a lot of transfusions)
-frozen RBC (rare)
-leukocyte-reduced RBC (Good for someone who has decreased immune fx ie someone with advanced HIV)
Washed and leukocyte reduced both decrease risk of rxns.
ffp
Plasma always frozen, skinny bag, little volume, defrosts quick.
platelets
for platelet disorders
Clotting factor deficiencies
Cancer patients receiving radiation and chemotherapy
Severely undernourished people
albumin
liver failure pt, someone who has low plasma proteins
cryoprecipitates
clotting factors. ie hemophiliacs
Transfusion methods
- homologous (most common type)
- typical blood transfusion from blood bank - designated, directed blood
- when family wants to give blood to a family member (but takes 2-3 days to test blood and everything still) - autologous *safest, least likely for a rxn
- preop: pt gives blood to self ie for elective surgery, maybe take some blood 5 wks prior
- periop: during surgery, save blood coming from pt, putting it back in
* only possible rxn: sepsis if it somehow gets contaminated.
- postop: common with ortho surgery. put a drain into surgical site, drains into a box and there’s something in there to keep blood from clotting, and if pt blood gets too low then they take the blood from the box.
therapeutic apheresis
take blood out of donor, run it thru machine that separates portions of blood, and rest of blood is sent back to pt.
separates out platelets, wbc, stem cells.
we get just what we need without depleting pt blood supply.
NRSG assess for transfusions
- Transfusion hx: more they’ve had, more susceptible they are to transfusion rxn (watch extra closely)
- Vital signs, lung sounds
- any health problems
- verify order (ALWAYS check blood with another licensed nurse)
- test compatibility
- examine blood bag for ID
- check exp date
- inspect blood for discoloration, gas bubbles, cloudiness
equipment prep for transfusion
- 16-20 gauge catheter (anything smaller will lyse RBC, and tubing will be clogged if too small)
- Y-type blood tubing with in-line filter: one spike goes into blood, one into NS. (blood is ALWAYS given with NS ONLY! not 1/2 NS, not dextrose with NS, nothing else)
- This tubing allows priming with saline, then start blood flow. Also, if rxn, have option to start blood and immediately start running NS.
- Optional equipment
- electronic infusion pump (impt, makes sure blood runs not too slow, not too fast. ~150, but start at abt 100 for first 15-30min and stay with them, then pump it up and check on them later)
- pressure cuffs
- blood warmers
nrsg consideration for timing:
have 30 mins to use blood after taking it from blood bank, or else send it back. cannot leave it in fridge on ur floor (not as reliable).
whole 350 mL should be given less than 4 hrs, so u have 3.5 hrs ish.
when should pt call u for blood transfusion
ANYTHING
chills, itchiness, diff breathing, small tingling