blood transfusion Flashcards

1
Q

Complex mixture of cells, water, proteins, and
sugars

A

Blood

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2
Q

process of donating own blood

A

autologous

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3
Q

friend or family member of the patient donates the blood

A

Directed

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4
Q

also known as autologous blood salvage.
procedure involving recovering blood lost during surgery and re infusing it into the patients

A

Intraoperative blood salvage

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5
Q

transfusion method that may be done induction of anesthesia.
blood obtained is then re infused after surgery

A

Hemodilution

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6
Q

Types of blood donation

A

Directed
Autologous
Intraoperative blood salvage
hemodilution

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7
Q

complications of blood donations

A
  1. excessive bleeding at venipuncture site
  2. Fainting
  3. Anginal chest pain
  4. Seizures
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8
Q

the most important blood type system (or
blood group system) in human blood
transfusion.
it identifies which sugars are present on the membrane of a person’s erythrocytes.

A

ABO system

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9
Q

are transmembrane proteins with
loops exposed at the surface of red blood cells.

A

Rh system

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10
Q

process of transferring blood or blood-
based products from one person into the
circulatory system of another

A

Blood transfusion

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11
Q

2 main types of blood transfusion

A

Homologous transfusions
Autologous Transfusions

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12
Q

The transfusion must begin within -—minutes

A

30 minutes

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13
Q

are sometimes given before the transfusion to
prevent other types of transfusion reactions.

A

Acetaminophen or Antihistamines

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14
Q

Principles of blood transfusions

A
  1. Proper refrigeration
  2. Proper typing and cross matching
    3.Aseptically assemble all materials needed for BT
  3. Ask another RN to recheck
  4. Check the blood unit for bubbles cloudiness,sediments and darkness in color
  5. BT should be completed less than 4 hours
  6. Avoid mixing or administering drugs at BT line
  7. Monitor strictly vital signs
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15
Q

Expiration of packed RBC is

A

3-6 days

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16
Q

Expiration of platelet is

A

3-5 Days

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17
Q

How many percent of population is RH postive

A

85%

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18
Q

Universal recipient

A

Type AB

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19
Q

Universal blood donor

A

Type O

20
Q

Diseases transmitted by blood transfusions

A
  1. Viral Hepatitis
    2.AIDS (HIV and HTLV)
  2. Cytomegalovirus (CMV)
  3. Graft versus Host Disease (GVHD)
  4. Creutzfeldt-Jakob Disease (CJD)
21
Q

Avirus that infects most people worldwide.

virus that infects most people worldwide.
spreads from person to person by direct
contact.

A

Cytomegalovirus(CMV)

22
Q

A rare disorder that can strike persons whose immune system is suppressed and have either received a blood transfusion or a bone marrow
transplant.

A

Graft versus Host Disease (GVHD)

23
Q

A dementing disease of the brain caused by an unconventional, transmissible agent (prion).

A

Creutzfeldt-Jakob Disease (CJD)

24
Q

graft-versus-host-disease is divided
into:

A
  1. acute or fulminant form
  2. chronic form
25
Q

normally observed within the first 100 days post-transplant

A

Acute or fulminant form

26
Q

Normally occurs after 100 days

A

chronic form

27
Q

plasma consisting of:

A

-water
- proteins
- salts
- nutrients
- vitamins
- hormones

28
Q

blood cells consisting of:

A
  • RBCs
  • WBCs
  • Platelets
29
Q

Clear liquid made up of 92% water and 8%
organic & inorganic biochemical

A

plasma

30
Q

provides all components
(Hct = 40%)

A

Whole blood

31
Q

Provide almost twice the amount of Hct than whole blood

A

Packed Red Blood Cell (PRBC)

32
Q

Contains all coagulation factors including V & VIII

A

Fresh Frozen Plasma

33
Q

contains von Wilebrand factor, factor VIII, XIII & fibrinogens

A

Factor VIII Fractions (Cryoprecipitate)

34
Q

Do not increase WBC: increase marginal pool (at tissue level) rather than circulating pool

A

Granulocytes

35
Q

Shaking chills or rigors common, require brief
cessation of therapy, administration of
meperidine IV until rigors are diminished &
resumption of transfusion when symptoms
relieved

A

Granulocytes

36
Q

A glycoprotein hormone produced by the
kidney, that controls erythropoiesis, or red
blood cell production.

A

Erythropoietin

37
Q

also known as Eprex) or
NeoRecormon)

A

epoetin

38
Q

is associated with an increased
risk of adverse cardiovascular complications in
patients with kidney disease if it is used to
increase hemoglobin levels above 13.0 g/dl.

A

erythropoietin

39
Q

Used to increase the number of hematopoietic
stem cells in the blood of the donor before
collection by leukapheresis for use in
hematopoietic stem cell transplantation.

A

Granulocyte-Colony Stimulating Factor

40
Q

protein secreted by macrophages, T cells,
mast cells, endothelial cells and fibroblasts.

A

Granulocyte-Macrophage Stimulating Factor

41
Q

stimulates the production and differentiation of megakaryocytes, the bone marrow cells that fragment into large numbers of platelets

A

Thrombopoietin

42
Q

PHARMACOLOGIC ALTERNATIVES TO BT

A

1.Growth Factors
2.Erythropoietin
3. Granulocyte-Colony Stimulating Factor
4.Granulocyte-Macrophage Stimulating Factor
5. Thrombopoietin

43
Q

Brand Name of Granulocyte-Colony Stimulating Factor

A

Neupogen

44
Q

Trade name of Granulocyte-Macrophage Stimulating Factor

A

Leukine

45
Q

Plasma proteins

A

Albumin
globulin
fibrinogen
prothrombin