Blood Top 100

Question 1

Examples of anti-platelets

Answer 1

Clopidogrel, prasugrel, ticagrelor

Question 2

Communication to pt regarding anti-plts

Answer 2

Bleeding - seek advice

Stop 7 days before surgery

Question 3

Aspirin SE

Answer 3

GI irritation - ulcers, bleeding
bronchospasm
high dose - tinnitus

Question 4

Aspirin communication to patient

Answer 4

take with food

Question 5

Aspirin CI

Answer 5

<16, senstivity, 3rd trimester, careful in gout

Question 6

Examples of DOACs

Answer 6

Apixiban, dabigatran, edoxaban, rivaroxaban

Question 7

CI to DOAC

Answer 7

Pregnancy + breastfeeding

Question 8

Advantages of DOAC

Answer 8

ORAL - unlike heparin.

Question 9

What DOAC MUST be taken with food?

Answer 9

Rivoroxaban

Question 10

What is B1?

Answer 10

Thiamine - alcohol - pabrinex

Question 11

When is folic acid given?

Answer 11

pregnancy

megaloblastic aanemia

Question 12

What is hyodroxobalamin?

Answer 12

B12 - megaloblastic anaemia and SDSC

Question 13

Dose of folic acid for pregnancy normally and also for higher risk?

Answer 13

400mcg

5MG for high risk

Question 14

name for vitamin K

Answer 14

Phytomenadione

Question 15

preventing VTE in AF with prosthetic valves and those with non-valvular AF

Answer 15

Non valvular AF - DOAC

Prosthetic - warfarin

Question 16

Warfarin and pregnancy

Answer 16

Not in first trimester, also avoid later in pregnancy as risk of bleeding

Question 17

Types of heparin

Answer 17

Enoxaparin, dalteparin fondaparinux

UFH

Question 18

examples of LMWH

Answer 18

Dalteparin, enoxaparin

Question 19

Administration of heparin

Answer 19

SC

Question 20

Monitoring of heparins

Answer 20

LMWH/fondaparinux - not really require monitoring. If higher risk may do - renal impairment or pregnancy - anti factor Xa activity plasma.
UFH - less predictable so needs monitoring
APTR and at start of therapy –> FBC, clouting, renal,
prolonged therapy monitor potassium and platelets - risk of HIT