Blood sugar regulation Flashcards
Role of liver
Receives glucose via Hepatic portal vein after being absorbed into blood through walls of small intestine.
Removes glucose from blood to provide energy for its functioning.
Converts glucose into glycogen for storage.
Continues sending glucose to circulate as a source of energy for body cells.
Converts large amounts of excess to fat for long term storage.
Glycogenesis
Converts glucose into glycogen. Is stimulated by Insulin.
Glycogenolysis
Breaks down glycogen into glucose. Stimulated by glucagon.
Lipogenesis
Converts glucose into fat in adipose tissue. Causes increase in protein synthesis in cells. Stimulated by Insulin.
Gluconeogenesis
Converts fat + amino acids into glucose. Stimulated by glucagon.
Role of pancreas
Islets of Langerhans
Cluster of hormone secreting cells in Pancreas.
Alpha cells – secretes Glucagon
Beta cells – secretes Insulin
Glucagon
Increases blood sugar.
Stimulates glycogenolysis (glycogen → glucose) in liver.
Stimulates gluconeogenesis (fats + amino acids → glucose)
Insulin
Decreases blood sugar.
Stimulates glycogenesis (glucose → glycogen) in liver and muscles.
Increases uptake of glucose from blood into body cells + protein synthesis.
Stimulates lipogenesis (glucose → fat).
Increase blood sugar feedback loop
Decrease blood sugar feedback loop
Role of adrenal glands
Adrenaline
Increases blood sugar.
Stimulates glycogenolysis (glycogen → glucose).
Converts glycogen → lactic acid → glucose.
Cortisol
Increases blood sugar.
Stimulates glycogenolysis (glycogen → glucose) in liver.
Stimulates gluconeogenesis (fats + amino acids → glucose).
Removal of amino acids from muscle cells.
Increase blood sugar feedback loop - Adrenal glands