Blood reference ranges Flashcards

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1
Q
  • What is ALT and AST?

-Their indication if raise

  • causes
  • What does AST:ALT ratio do?
A
  • Alanine aminotransferase (ALT) and aspartate aminotransferase (AST)
  • raise cause liver cell inflammation or damage, indicates of hepatocellular injury
  • Hepatitis, liver cirrhosis, drug/toxin-induced liver injury, malignancy
  • 2:1 ratio are classical of alcoholic liver disease
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2
Q
  • What is ALP and origin?
  • causes
  • What is GGT and marker of ________
  • ALP rise + normal GGT indicates?
  • ALP raise + rise GGT indicates?
  • Isolated GGT rise indicates?
A
  • alkaline phosphatase (ALP); biliary epithelial cells and bones
  • cholestasis / bone disease
  • Gamma-glutamyltransferase (GGT); marker of liver damage and cholestasis
  • bone disease (e.g. Paget’s disease, vitamin D deficiency, bony metastases)
  • cholestasis
  • alcohol excess
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3
Q

normal range of the following:
- ALT
- AST
- ALP
- GGT
- bilirubin
- Albumin

A

ALT 3-40 IU/L
AST 3-30 IU/L
ALP 30-100 IU/L
GGT 8-60 IU/L
Bilirubin 3-17 μmol/L
Albumin 35-50 g/L

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4
Q

jaundice is present with what level of bilirubin?

A

more than 50 micromol/L

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5
Q

range of following WBC
- Total WBC
- Neutrophils
- Lymphocytes
- Monocytes
- Eosinophils
-Basophils

A

Total: 3.6 – 11.0 x 109/L
Neutrophils: 1.8 – 7.5 x 109/L
Lymphocytes: 1.0 – 4.0 x 109/L
Monocytes: 0.2 – 0.8 x 109/L
Eosinophils: 0.1 – 0.4 x 109/L
Basophils: 0.02 – 0.10 x 109/L

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6
Q

Range of Mean cell volume (MCV)

A

80 – 100 fL

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7
Q

Range of:
- prothrombin time (PT) / INR

  • Activated partial thromboplastin time (APTT)
  • Fibrinogen
  • D-dimer
A
  • 10 – 14 seconds
  • 24 – 37 seconds
  • 1.50 – 4.50 g/L
  • < 500 ng/mL
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8
Q

Hematinic:

  • Ferritin (M&F)
  • Vitamin B12
  • Folate
  • Iron (M&F)
  • Transferrin
A
  • ♂ 25 – 350 ng/mL
    ♀ 10 – 300 ng/mL
  • 180 – 1000 pg/mL
  • > 4.0 ng/mL
  • ♂ 11.6 – 35.0 μmol/​L
    ♀ 4.6 – 30.4 μmol/​L
  • 2.0 – 3.6 g/L
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9
Q

What is the normal range of CRP?

A

< 5mg/L

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10
Q
A
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