Blood, Hemostasis, and Blood Groups Flashcards
What type of tissue is blood considered?
Connective. because of extracellular matrix surrounded.
Only fluid tissue of the body
What percent of our body weight is blood?
8%. 5-6 in men/ 4-5 in women
What should the pH be between?
7.35 and 7.45
Why would the color of the blood be dark?
Deoxygenation- when O2 is unloaded
Low O2
Why would the color of the blood be dark?
Low O2
What is hemocrit and the normal value between?
percentage of blood volume that consists of erythrocytes. Normal value 45(+/-5%)
Blood functions?
Distribution of respiratory gases, nutrients and metabolic waste products
Hormone transport
Regulates body temp, body pH and total blood volume
Protection against infections
Plasma?
Liquid part of blood
55% of blood volume
Formed Elements?
RBC
WBC
Platelets
Blood Plasma?
Consists of 90% water acting as a solvent for other substances
Proteins being the majority of “other substances”
-produced by the liver
What 3 groups are blood plasma divided into?
Albumins
Globulins
Other solutes- nutrients, electrolytes, gases, hormones, and metabolic wastes
Erythrocytes?
transport if oxygen from the lungs to the tissue
depending on hemoglobin
No nucleus or mitochondria. Cannot use the oxygen to generate ATP
Life span of 100-120 days
Hemocytoblast?
blood cell formation
Hemopoiesis/ Hematopoiesis
production of all formed elements occurring in red bone marrow
driven by influence of hormones and growth factors depending on the needs of the body
Type O
neither A nor B antigens, naturally makes antibodies against both therefore cannot receive from anyone other than O
-universal donor
AB Blood
-both A and B antigens, making no antibodies or it would attack itself
-Universal recipient
Type A
A antigens and naturally makes antibodies against B antigen
Type B
B antigens and naturally makes antibodies against A antigen
Rh antigen
Considered +, if not then you are -
-Antibodies are only formed after exposure (during birth or via transfusin)
Hemoglobin
4 chains; 2 alpha and 2 beta
carrying 4 O2 molecules
can bind to other gases
bind with CO2 to form carbaminohemoglobin
Hemoglobin
4 chains; 2 alpha and 2 beta
carrying 4 O2 molecules
can bind to other gases
bind with CO2 to form carbaminohemoglobin
Hypoxia and its normal values
Lack of RBC leading to oxygen deficiency in tissues
-Men 16 (+/-2)
-Women 14 (+/-2)
Anemia
abnormal low hemoglobin
fatigue, paleness, shortness of breath, chills
Aplastic Anemia
low # of RBC
caused by destruction or inhibition of red bone marrow
