blood groups

Question 1

IgG

Answer 1

Rh, Ss, Kell, Kidd, Duffy
* they are also immunogenic

Question 1

IgM

Answer 1

ABO, Li, P1, P2, Pk,P, MN, -I, HI, -IA, -H, -A1
* they are also naturally occuring

Question 2

Dosage

Answer 2

Rh, MN, Ss, Duffy

Question 3

Autoantibodies

Answer 3

-H, -I, -HI, -AI, P, P2

Question 4

bind complement to C9

Answer 4

ABO, Lewis, Kidd

Question 5

bind complement to C3

Answer 5

Kell, Duffy, P1, -I

Question 6

which antigens are enhanced by enzymes

Answer 6

ABO, Rh, P, P1, Kidd, Lewis, Ii

Question 7

which antigens are destroyed by enzymes

Answer 7

Duffy, Xga, Cha, Rga, Ss, MN

Question 8

what antigen is neither enhanced or destroyed by enzymes?

Answer 8

Kell

Question 9

transfusion tool box includes

Answer 9

• enzymes
• HLTA
• DTT
• dissociation
• elutions

Question 10

IS

Answer 10

ABO, Ii, P, Lewis

Question 11

IAT

Answer 11

ABO, Rh, Kell, Kidd, Duffy, Xga, MNS

Question 12

antigens destroyed by routine enzymes

Answer 12

Duffy, Xga, Ss

Question 13

antigens destroyed by ZZAP/WARM

Answer 13

Kell, Ss,

Question 14

ZZAP/ WARM is made out of…

Answer 14

papain
- comes from papaya see
dithiothreitol
- destroys Kell antigen

Question 15

what antigens are indirect gene products produces by transferases?

Answer 15

ABO, I, Lewis, P

Question 16

what is chido rodgers

Answer 16

high incidence antigens
high titre low avidity (not too many sites causing a weak reaction)
are destroyed by enzymes - but is also tested by enzymes

Question 17

what is the vel antigen

Answer 17

high incidence antigen
enhanced by enzymes
clinically insignificant

Question 18

what is Sid antigen

Answer 18

• cause a weak reaction with mix field agglutination
• 96% of people positive for Sd antigen
• has the same proteins as Tamms horsfall
  neutralization of Sda plasma with guinea pig
  urine: antibody will bind to the proteins to guinea pif antigen