BLOOD GROUP SYSTEMS Flashcards

1
Q

Enzymes responsible for the synthesis of glycan
chains on mucins by transferring sugar residues
to specific acceptors

A

GLYCOSYLTRANSFERASES

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2
Q

contribute to cell recognition
and the immune response

A

Glycans

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3
Q

What antigens are created by glycosyltransferase?

A

A and B antigens

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4
Q

Antigens under this are formed by the action of
a-4 galactosyltransferase

A

P1PK

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5
Q

The antigens under P1PK are formed by the action of
_________________?

A

a-4 galactosyltransferase

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6
Q

The antigens present in LEWIS are mainly involved in _________ that aFFECTS BACTERIAL ADHESION

A

Mucosal immunity

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7
Q

Lewis antigens serve as a receptor for ________________?

A

Helicobacter pylori

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8
Q

Antigens present are mainly involved in mucosal
immunity that affects bacterial adhesion

A

Lewis

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9
Q

Precursor of A and B antigens

A

H

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10
Q

What are the 2 proteins present in MNS under structural relationship to red cells?

A

Glycophorin A and Glycophorin B

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11
Q

The function of this is to o maintain the net negative charge of RBCs

A

Sialic acid

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12
Q

Contains Band 3 protein (anion exchanger)
which plays a critical role in maintaining RBCs
structure

A

DIEGO

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13
Q

What do DIEGO contains?

A

Band 3 protein

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14
Q

What is Band 3 protein?

A

An anion exchanger

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15
Q

Associated with Glycophorin C which provides
structure for RBC (C for cytoskeleton). This
glycophorin stabilizes RBCs membrane

A

GERBICH

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16
Q

Gerbich is associated with _________________ which provides
structure for RBC (C for cytoskeleton). This
glycophorin stabilizes RBCs membrane

A

Glycophorin C

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17
Q

provides structure for RBC (C for cytoskeleton). This glycophorin stabilizes RBCs membrane

A

Glycophorin C

18
Q

Mainly involved in ammonia and gas transport
in RBCs

19
Q

Important for urea transport

20
Q

Expressed on Aquaporin 1 which controls
water permeability

21
Q

Affects the RBC membrane stability

22
Q

Associated with complement component 4
(C4) which is mainly involve in immune
response

A

CHIDO RODGERS

23
Q

Chido Rodgers is associated with complement ________________ which is mainly involve in immune
response

A

component 4 (C4)

24
Q

Linked to Decay-accelerating factor (DAF)
which regulates complement activation and
provides protection for RBCs from
destruction

25
Cromer is linked to _____________________ which regulates complement activation and provides protection for RBCs from destruction
Decay-accelerating factor (DAF)
26
Involves complement receptor 1 (CR1) which is for immune complex clearance
KNOPS
27
Associated with Basal Cell Adhesion Molecule (BCAM) which is involve in adhesion to extracellular matrix
LUTHERAN
28
Lutheran is associated with ______________ which is involve in adhesion to extracellular matrix
Basal Cell Adhesion Molecule (BCAM)
29
Involved in cell adhesion but their functions are not well understood
XG
30
It has an interaction with intracellular adhesion
LANDSTEINER WIENER
31
Involved in Cluster of Differentiation 44 (CD44) which is for cell migration and cell adhesion
INDIAN
32
Antigens under this acts as a receptor for Plasmodium vivax (P. vivax)
DUFFY
33
Antigens under Duffy, acts as a receptor for __________________?
Plasmodium vivax
34
If you have an antibody against the Duffy antigen, you are resistant to ___________?
Malaria
35
Function as cytokine receptors
Duffy
36
has a function of regulating inflammatory or immune response
Cytokine
37
Involve in immune complex clearance
KNOPS
38
Expressed on CD44 (cell migration and cell adhesion)
indian
39
Responsible for the initial conversion of precursor substances into Lea
Le (FUT3) gene
40
If present along with Le, it further modifies Lea into Leb
Se (FUT2) gene
41
Test used to recover or detect H. pylori infection
UREA BREATH TEST