BLOOD GROUP SYSTEMS Flashcards
Enzymes responsible for the synthesis of glycan
chains on mucins by transferring sugar residues
to specific acceptors
GLYCOSYLTRANSFERASES
contribute to cell recognition
and the immune response
Glycans
What antigens are created by glycosyltransferase?
A and B antigens
Antigens under this are formed by the action of
a-4 galactosyltransferase
P1PK
The antigens under P1PK are formed by the action of
_________________?
a-4 galactosyltransferase
The antigens present in LEWIS are mainly involved in _________ that aFFECTS BACTERIAL ADHESION
Mucosal immunity
Lewis antigens serve as a receptor for ________________?
Helicobacter pylori
Antigens present are mainly involved in mucosal
immunity that affects bacterial adhesion
Lewis
Precursor of A and B antigens
H
What are the 2 proteins present in MNS under structural relationship to red cells?
Glycophorin A and Glycophorin B
The function of this is to o maintain the net negative charge of RBCs
Sialic acid
Contains Band 3 protein (anion exchanger)
which plays a critical role in maintaining RBCs
structure
DIEGO
What do DIEGO contains?
Band 3 protein
What is Band 3 protein?
An anion exchanger
Associated with Glycophorin C which provides
structure for RBC (C for cytoskeleton). This
glycophorin stabilizes RBCs membrane
GERBICH
Gerbich is associated with _________________ which provides
structure for RBC (C for cytoskeleton). This
glycophorin stabilizes RBCs membrane
Glycophorin C
provides structure for RBC (C for cytoskeleton). This glycophorin stabilizes RBCs membrane
Glycophorin C
Mainly involved in ammonia and gas transport
in RBCs
RH
Important for urea transport
KIDD
Expressed on Aquaporin 1 which controls
water permeability
COLTON
Affects the RBC membrane stability
KX
Associated with complement component 4
(C4) which is mainly involve in immune
response
CHIDO RODGERS
Chido Rodgers is associated with complement ________________ which is mainly involve in immune
response
component 4 (C4)
Linked to Decay-accelerating factor (DAF)
which regulates complement activation and
provides protection for RBCs from
destruction
CROMER