BLOOD GAS Flashcards

1
Q
A
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2
Q

Normal blood pH

A

7.35-7.45

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3
Q

Enzyme need to convert Carbonic Acid to Bicarbonate ion?

A

Carbonic Anhydrase

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4
Q

Dissociated of H2CO3 __________ in HCO3 causing it to _____ into the plasma

A
  1. Increased
  2. Diffuse
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5
Q

Ratio of Bicarbonate ion to Carbonic Acid

A

20:1

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6
Q

If CO2 doesn’t excreted, what will happen?

A

There’s an increase og H+ ion concentration which leads to acidic pH or acidosis.

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7
Q
A
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8
Q

rapid or fast removal of CO2 by the lungs

A

Decreas the H+ ion concentration which leads to respiratory alkalosis.

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9
Q

Function of Kidneys

A

To excrete acid

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10
Q

How many acid must be excreted daily by the kidney

A

50-100 mmol/L

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11
Q

buffering
effects of hemoglobin causing venous
blood to be 0.03 unit lower in pH

A

chloride-isohydric shift

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12
Q

each Celsius above 37°:

A

↑ pH by 0.015

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13
Q

optimum pH for arterial blood

A

7.40

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14
Q

TO MAINTAIN pH

A
  1. neutralize acid as they are generated
  2. elimination of the acid permanently
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15
Q
A
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16
Q

Factors that causes Bicarbonate to increase

A

IV infusion of lactate, acetate and HCO3-

17
Q

Factors that causes Bicarbonate to decrease

A

Diuretics, reduced reabsorption, chronic nephritis

18
Q

Urinary excretion of HCO3

A

26 – 30 mmol/L

19
Q

Normal excretion rate of bicarbonate

A

10 mEq/day

20
Q

Ceased excretion of HCO3-

A

↓ 25 mmol/L

21
Q

Major extracellular blood buffer

A

Carbonic Acid & bicarbonate

22
Q

Weak acid/ base blood buffer

A

Plasma proteins

23
Q

02 carry blood buffer

A

Hemoglobin

24
Q

1 gram hemoglobin carries

A

1.39 ml of oxygen

25
Q

1 mole of hemoglobin binds

A

1 mole of oxygen

26
Q

1st line of defense against pH

A

Chemical buffer system:
1. Bicarbonate
2. Phosphate
3. Proteins

27
Q

2nd line of defense against pH

A

Physiologic Buffer System