Blood films Flashcards
What is anisocytosis and where is it seen?
Increased variation in size
In micro/macrocytosis
What is poikilocytosis?
Increased variation in shape
What is spherocytosis and where is it seen?
Small spherical, lack central pallor
Hereditary spherocytosis, Warm AIHA
What is sickle cell and where is it seen?
Crescenteric, sickle-cell anaemia
What is target cells and where is it seen?
Central and peripheral staining
Iron deficiency, sickle cell, thalassaemia
What are tear drop cells and where is it seen?
Tear drop shaped
Myelofibrosis, extramedullary haemopoeisis
Where are elliptocytes seen?
Elliptocytosis
What are eckinocytes and when are the
Long projections from surface
Renal disease
What acanthocytes and when are they seen
PK deficiency, liver disease, splenectomy
When are fragments seen?
DIC, microangiopathy, mechanical valve replacement
What are Howell-Jolly bodies and when are they seen?
Small nuclear incisions (rate bites)
Splenectomy, hyposplenism
What are Heinz bodies and when are they seen?
Precipitates of oxidized denatured Hb
G6PD deficiency
What is roleaux and when is it seen?
Red cell stacking (like coins)
Multiple myeloma, Waldenström’s macroglobulinaemia