blood films Flashcards
1
Q
What is heinz bodies associated with?
A
G6PD deficiency: it is the most common red cell enzyme defect. It is a x-linked recessive condition associated with increased red cell susceptibility to oxidative stress,
Haemolysis can be triggered by infection, drugs and broad beans.
Drugs include-ciprofloxacin, antimalarials-PRIMAQUINE, sulpa group- sulphonamides, sulphonylureas, sulfazalazine
Blood film also shows blister cells and bite.
Typical hx- neonatal jaundice, jaundice during illness, gallstones
2
Q
what are smudge cells associated with
A
b cell chronic lymphocytic leukaemia
3
Q
what are schistocytes asssociated with
A
microangiopathic haemolytic anaemia
Other features include-
normocytic anaemia
thrombocytopenia
