Blood film Flashcards
Target cells
- Sickle Cell
- Haemoglobinopathies
- Hyposplenism
- ID anaemia
- Thalassaemia
- Liver disease
- Post-splenectomy
Pencil cells
Iron deficiency anaemia
Hypochromic/microcytic cells
TAILS
Hypersegmented nuclei
Megaloblastic anaemia: B12/folate deficiency
Agglutination
Cold autoimmune haemolytic anaemia
Rouleaux
Myeloma
Reed sternberg cells
Hodgkin’s lymphoma
Basophilic stippling/inclusion bodies?
Let Tanisha Sing More (all about that bass)
- Lead poisoning
- Thalassaemia
- Sideroblastic anaemia
- Myelodysplasia
Signet rings?
Malaria
Atypical lymphocyte?
Infection (EBV)
Tear drop cells
Myelofibrosis
Heinz bodies
G6PD deficiency
Alpha-thalassaemia
They are RBC inclusions of denatured Hb, occur due to oxidant damage
Bite cells
G6PD deficiency
Leukoerythroblastic film
- Bone marrow infiltrarion
- myelofibrosis
- sepsis
- haemolysis
Auer rods?
AML
Howell Jolly bodies?
- Post-splenectomy
- Leukaemia
- Thalassaemia
- Pernicious anaemia
- Haemolytic anaemia
- Hyposplenism
Acanthocyte
- Splenectomy
- Leukaemia
- Thalassaemia
- Pernicious anaemia
- Haemolytic anaemia
- Liver disease
- Renal failure
- Abetalipoproteinemia???
Spherocytes/elliptocytes?
Hereditary spherocytosis
Autoimmune hemolytic anaemia
Macrocyte
- Liver disease
- alcoholism
- Oval in megaloblastic anaemia
Fragments
- DIC
- microangiopathy
- HUS
- TTP
- burns
- cardiac valves
Nucleated RBC?
- Acute haemolysis
- Bone marrow infiltration in malignancy
- similar in size to RBCs, have pink cytoplasm and condensed nucleus
What is a monocyte?
- Largest WBC in peripheral blood
- cytoplasm lacks granules
- indented nucleus
- precursor to macrophages
Monocytosis seen in?
- Infections e.g. TB, malaria, brucellosis, infective endocarditis
- Myelodysplasia
- Hodgkin’s lymphoma
- Monocytic leukaemia
Schistocytes (helmet cells)?
- Mechanical heart valve
- Intravascular haemolysis
- DIC
Burr cells? (echinocytes)
- Uraemia
- Pyruvate kinase deficiency
Smudge/smear cells?
CLL
