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Tan Haematology > Blood film > Flashcards

Blood film Flashcards

1
Q

Target cells

A
  • Sickle Cell
  • Haemoglobinopathies
  • Hyposplenism
  • ID anaemia
  • Thalassaemia
  • Liver disease
  • Post-splenectomy
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2
Q

Pencil cells

A

Iron deficiency anaemia

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3
Q

Hypochromic/microcytic cells

A

TAILS

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4
Q

Hypersegmented nuclei

A

Megaloblastic anaemia: B12/folate deficiency

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5
Q

Agglutination

A

Cold autoimmune haemolytic anaemia

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6
Q

Rouleaux

A

Myeloma

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7
Q

Reed sternberg cells

A

Hodgkin’s lymphoma

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8
Q

Basophilic stippling/inclusion bodies?

A

Let Tanisha Sing More (all about that bass)

  • Lead poisoning
  • Thalassaemia
  • Sideroblastic anaemia
  • Myelodysplasia
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9
Q

Signet rings?

A

Malaria

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10
Q

Atypical lymphocyte?

A

Infection (EBV)

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11
Q

Tear drop cells

A

Myelofibrosis

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12
Q

Heinz bodies

A

G6PD deficiency
Alpha-thalassaemia

They are RBC inclusions of denatured Hb, occur due to oxidant damage

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13
Q

Bite cells

A

G6PD deficiency

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14
Q

Leukoerythroblastic film

A
  • Bone marrow infiltrarion
  • myelofibrosis
  • sepsis
  • haemolysis
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15
Q

Auer rods?

A

AML

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16
Q

Howell Jolly bodies?

A
  • Post-splenectomy
  • Leukaemia
  • Thalassaemia
  • Pernicious anaemia
  • Haemolytic anaemia
  • Hyposplenism
17
Q

Acanthocyte

A
  • Splenectomy
  • Leukaemia
  • Thalassaemia
  • Pernicious anaemia
  • Haemolytic anaemia
  • Liver disease
  • Renal failure
  • Abetalipoproteinemia???
18
Q

Spherocytes/elliptocytes?

A

Hereditary spherocytosis
Autoimmune hemolytic anaemia

19
Q

Macrocyte

A
  • Liver disease
  • alcoholism
  • Oval in megaloblastic anaemia
20
Q

Fragments

A
  • DIC
  • microangiopathy
  • HUS
  • TTP
  • burns
  • cardiac valves
21
Q

Nucleated RBC?

A
  • Acute haemolysis
  • Bone marrow infiltration in malignancy
  • similar in size to RBCs, have pink cytoplasm and condensed nucleus
22
Q

What is a monocyte?

A
  • Largest WBC in peripheral blood
  • cytoplasm lacks granules
  • indented nucleus
  • precursor to macrophages
23
Q

Monocytosis seen in?

A
  • Infections e.g. TB, malaria, brucellosis, infective endocarditis
  • Myelodysplasia
  • Hodgkin’s lymphoma
  • Monocytic leukaemia
24
Q

Schistocytes (helmet cells)?

A
  • Mechanical heart valve
  • Intravascular haemolysis
  • DIC
25
Q

Burr cells? (echinocytes)

A
  • Uraemia
  • Pyruvate kinase deficiency
26
Q

Smudge/smear cells?

A

CLL

Tan Haematology (5 decks)

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