Blood film Flashcards

1
Q

What conditions are the following blood film appearances associated with: target cells?

A

Hyposplenism/splenectomy

Iron deficiency anaemia

Sickle cell/thallasemia

Liver disease

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2
Q

What conditions are the following blood film appearances associated with: schistocytes?

A

Intravascular haemolysis

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3
Q

What conditions are the following blood film appearances associated with: ‘pencil’ poikilocytes?

A

Iron deficiency anaemia

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4
Q

What conditions are the following blood film appearances associated with: hypersegmented neutrophils?

A

Macrocytic anaemia

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5
Q

What conditions are the following blood film appearances associated with: Pappenheimer bodies?

A

Hyposplenism/splenomegaly

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6
Q

What conditions are the following blood film appearances associated with: Howell-Jolly bodies?

A

Hyposplenism/splenomegaly

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7
Q

Which condition is associated with itching after exposure to warm water?

A

Polcythaemia Vera

Excess red cells predisposes to clotting.
Itching sue to inappropriate release of histamine.

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8
Q

In which condition are smudge cells found?

A

CLL

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9
Q

In which condition are Auer rods found?

A

AML

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10
Q

In which condition is JAK-2 mutation associated?

A

Polycythaemia Rubra Vera

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11
Q

In which conditions do you see basophillic stippling (purple dots within a RBC)?

A

Lead poisoning
Thalassaemia
Sideroblastic anemia
Myelodysplasia

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12
Q

Which condition is associated with t(9:22)?

A

CML: Philladelphia chromosome transolcation t(9:22)

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