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BLOOD BANK > Blood Donation > Flashcards

Blood Donation Flashcards

1
Q

Frequent plasma donors have a total serum protein of at least ___

A

6.0 g/dL

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2
Q

Plasmapheresis donors must have a serum protein electrophoresis or quanti immunodiffusion performed every __ months

A

4

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3
Q

Separates WBCs from RBCs during centrifuge in leukapheresis

A

Hydroxyethyl starch (HES)

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4
Q

Increases the number of circulating granulocytes

A

Corticosteroids & Colony stimulating factor (CSF)

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5
Q

Each unit of transfused RBCs is expected to increase Hb level __ and the Hct level __

A

1 g/dL
3%

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6
Q

In packed RBCs, __ of plasma is removed

A

80%

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7
Q

In packed RBCs, if CPDA-1 is used _____ of plasma can be removed

A

200-250 mL

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8
Q

Shelf life of irradiated RBCs

A

Orig outdate or 28 days from irradiation
whichever comes first

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9
Q

leukoreduced red cells, WBC count is reduced to ___ and contains at least ___ of the original RBC mass

A

5 x 10^6
85%

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10
Q

Blood needed for patients with history of allergic, febrile, urticarial & anaphylactic reactions

A

washed rbcs

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11
Q

RBC aliquot is transfused to __ containing __ of blood

A

neonates/infants
10-25 mL

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12
Q

In plateletpheresis, platelet ct must be at least

A

150,000/uL

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13
Q

Decreased pH, preventing caramelization

A

Citric acid

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14
Q

only FDA approved rejuvenation soln in US

A

Rejuvesol

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15
Q

Red cells stored in the liquid state for fewer than __ after their outdate are rejuvenated for __ hours at 37°C with the soln

A

3 days
1-4 hours

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16
Q

Pooled platelets
# of units:
Shelf life in open system:
Shelf life in closed system:

A

6-10 units
4 hours (open)
5 days (closed)

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17
Q

Platelet concentrate AKA

A

Random Donor Platelet (RDP)

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18
Q

Plateletpheresis AKA

A

Single Donor Platelet (SDP)

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19
Q

5.5 x 10^10 plts
pH > 6.2
1 unit ≈ ⬆️ plt by 5,000-10,000/uL

A

Platelet concentrate

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20
Q

3.0 x 10^11 plts
pH > 6.2
≈ 6-8 RDP
1 unit ≈ ⬆️ plt by 30,000-60,000/uL

A

Plateletpheresis

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21
Q

Frozen platelets

A

for research purposes
-80°C up to 2 years

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22
Q

Has plasma, all coag factors & complement EXCEPT PLTS

A

FFP

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23
Q

Not group specific

A

Cryoprecipitate

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24
Q

For TX of fibrinogen def, Hemophilia A, vWB dss, F XIII def

A

cryoprecipitate

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25
Q

Cryoprecipitate after thawing (unpooled)

A

6 hours

UNPOOL = 6

26
Q

Cryoprecipitate after pooling

A

4 hours

POOL= 4

27
Q

To control bleeding during surgery, fibrin glue is used which contains

A

Cryoprecipitate & Topical thrombin

28
Q

For TX of TTP

A

Cryosupernatant/cryopoor plasma

29
Q

After thawing Cryoprecipitate leave in room temp bc …

A

F VIII precipitates in refrigerator

30
Q

QC for cryoprecipitate

A

4 units monthly

31
Q

For those who are unresponsive to antibiotics

A

Granulocytes, pheresis

32
Q

Granulocytes, pheresis
Storage:
Shelf life:

A

Store at 20-24°C (RT) WITHOUT AGITATION
24 hours (due to disintegration)

33
Q

For preventing/control bleeding in Hemophilia A pxts

A

F VIII concentrate (lyophilized)

34
Q

For prevention/control bleeding in pxts with Hemophilia B

A

F IX concentrate (lyophilized)

35
Q

Replace loss of colloids, severe burns, for pressure support during hypotensive episodes

A

Albumin, Plasma protein fraction

36
Q

Albumin, Plasma protein fraction
Storage:
Shelf life:

A

2-10°C
5 years

37
Q

Treatment for HDN

A

Albumin, Plasma protein fraction

38
Q

min. dose of radiation for irradiation

A

25 Gy dose of gamma rad

39
Q

Irradiation is accomplished by using

A

cesium 137
cobalt 60

40
Q

Used to dilute blood components

A

5% albumin
isotonic (0.9%) saline

41
Q

Filter size that removes gross clots & cellular debris

A

170 to 260 um filter

42
Q

Filters used ONLY for RBCs

A

Micropore screen filter (20-40 microns)

43
Q

Filters used for both RBCs and platelets

A

Adsorption filter (adhesion)

44
Q

Red or Dark urine
DAT positive
as little as 10 mL

A

AIHTR

45
Q

⬆️ temp by 1°C or more
DAT negative

A

FNHTR

46
Q

Transfuse leukocyte reduced products to patients who have experienced ____ or more FNHTRs

A

2

47
Q

Donor’s plasma has foreign proteins

A

Allergic mild

48
Q

Rare and can present bronchoconstriction, angioedema, diarrhea
DAT negative
IgA deficiency (N IgA w/ anti-IgA)

A

Allergic severe (Anaphylactoid)

49
Q

IgA deficient w/ anti-IgA

A

Anaphylactic

50
Q

Transfuse ____ or platelets or frozen RBCs and plasma from IgA deficient donors

A

washed RBCs

51
Q

High concentrations of leukoagglutinins
severe hypoxemia
Bilateral infiltrates
NCPE

A

TRALI

52
Q

Prevention for TRALI

A

use male only plasma

53
Q

⬆️ of 2°C or more

A

Transfusion - associated sepsis

54
Q

Most common isolate in RBCs

A

Y. enterocolitica

55
Q

Pseudomonas found in RBCs units

A

P. putida
P. fluorescence

56
Q

Common isolate of human skin

A

P. acnes

57
Q

Gram + found in contaminated platelets

A

S. epidermidis
B. cereus

58
Q

Iatrogenic
rapid infusion of large volumes of blood products w/o equi blood loss
⬆️ BP
severe hypoxemia

A

TACO

59
Q

1 unit of RBC = __ of iron

A

250 mg

60
Q

Prevention of Iron overload

A

Hypertranfusions of neocytes

61
Q

Multiorgan failure

A

Iron overload

62
Q

Rash
Fever
Diarrhea
Pancytopenia

A

TA-GVHD

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