Blood disorders/heme Flashcards

1
Q

bleeding time: normal value, assessment

A
  • 3-10 minutes
  • plt function: ability to form platelet plug
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2
Q

plt count: normal value, assessment

A
  • 150,000-400,000
  • number not function; vascular integrity
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3
Q

PT: normal value, assessment

A
  • 10-14 sec
  • extrinsic (III, VII) and common pathways (I, II, V, X, XIII)
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4
Q

INR: normal value, assessment

A
  • 1
  • target with coumadin tx: 2-3
  • standardizes PT results, extrinsic and common pathways
  • specifically used to monitor coumadin
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5
Q

aPTT: normal value, assessment

A
  • 25-35 sec
  • intrinsic (VIII, IX, XI, XII) and common pathways (I, II, V, X, XIII)
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6
Q

ACT: normal value, assessment

A
  • 90-120 sec
  • intrinsic and common pathways
  • specifically used to monitor action of heparin
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7
Q

Thrombin time: normal value, assessment

A
  • 9-14 sec
  • time for fibrin clot to form
  • prolonged with low levels of fibrinogen
  • factors I, II
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8
Q

fibrinogen: normal value, assessment

A
  • 160-350
  • factor I
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9
Q

Coumadin inhibits which vitamin K dependent clotting factors?

A
  • II, VII, IX, X
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