Blood- Components, Hematopoeisis & Hemostasis Flashcards

1
Q

What are the 7 Main roles of Blood

A

Some of the most vital functions of Blood are : 1. Transportation of nutrition and respiratory gases and wastes 2. immunological function 3. Repair (blood platelets , clotting) 4. Messenger function 5. Regulating temperature 6. Regulating pH 7. Hydraulic function

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2
Q

Decreasing the venous return does what to : Blood Pressure

A

Decreases Blood Pressure

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3
Q

Decreased Cardiac Output does what to: blood pressure

A

Decreased blood pressure because there is less resistance

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4
Q

Increased vasoconstriction does what to resistance:

A

Increased resistance

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5
Q

Decreased blood viscosity to blood pressure:

A

Decreased blood pressure

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6
Q

Decreased sympathetic activity on blood pressure:

A

Decreased blood pressure

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7
Q

What is Cardiac Output

A

The volume of blood pumped by the heart per minute mL blood/min

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8
Q

What is Stroke volume ?

A

The volume of blood, in millimetres pumped out of the heart with each beat

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9
Q

What within Erythrocytes transports most of oxygen and part of the carbon dioxide.

A

Hemoglobin: oxygen binds to the heme on the hemoglobin molecule.

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10
Q

Normal levels of RBC’s in Hematocrit for Adult Males: Adult Females:

A

Adult Males: 40.7 to 50.3% Adult Females: 32 to 44.3. %

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11
Q

Why are hematocrit levels higher in makes than females ? (2)

A
  1. Testosterone stimulates the production of erythropoietin witch stimulates erythropoiesis ( the production of new erythrocytes) 2. Women during reproductive age lose blood during menstruation.
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12
Q

What is the life span of an erythrocytes and why is it short?

A

100-120 days because erythrocytes do not contain a nucleus they can not repair themselves when damaged

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13
Q

Why are erythrocytes the shape they are ( bi-concaved disks) ?

A

Increases the surface area of the cell thus increasing the efficiency of diffusion of oxygen and carbon dioxide

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14
Q

What are them main roles of WBC ?

A
  1. Help heal wounds by fighting infection and ingesting matter such as dead cells, debris and old RBC’s 2. Protection from foreign bodies 3. Protection against mutated cells such as cancers
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15
Q

What are the Role(s) of Neutrophils, when do they increase and what is a normal range to be found in the blood?

A

Neutrophils are one of the bodies main defences against bacteria, they ingest by phagocytosis ( consume the foreign invader).They increase rapidly during acute or short term infections A normal range of neutrophils is 40 to 70% of WBC

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16
Q

What are the Role(s) of Eosinophils, when do they increase and what is a normal range to be found in the blood?

A

Kill parasites by inundating them with digestive enzymes. The increase during a parasitic infection or allergies. A normal range found is 1-4%

17
Q

What are the Role(s) of Basophils and what is a normal range to be found in the blood?

A

Basophils release histamine which causes blood vessels to leak and attract WBC’s and heparin which prevents clotting in the infected area so that the WBC’s can reach the bacteria. A normal range is 0-1%

18
Q

What are the Role(s) of Monocytes , when do they increase and what is a normal range to be found in the blood?

A

Monocytes become macrophages in response to an infection or accumulating dead or damaged cells. Macrophages recognize, target and destroy target cells. Are increased in number during chronic infections. A normal range is 4-8%

19
Q

What are the Role(s) of Lymphocytes, and what is a normal range to be found in the blood?

A

Lymphocytes can recognize and have a memory of an invading bacteria and virus. T lymphocytes directly attack cells ( tumours, viruses ) and B lymphocytes produce antibodies

20
Q

What is Pictured?

A

A Neutrophil: Stains pale pink, with a deep purple nuculus consisting of three to seven lobes conected by thin strands

21
Q

What is pictured?

A

An Esinophile: Nuculus stains blue-red with a figure 8 shape

22
Q

What is pictured?

A

A Basophile: stains dark blue, has a granular apperance, nuculus is S or U shaped.

23
Q

What is pictured?

A

A Lymphocyte: Pale blue cytoplasm with a sperical nuculus stained dark purple-blue

24
Q

What is pictured?

A

A Monocyte: grey blue cytoplasm with a kidney shaped nucleus

25
Q

What is Hematopoeisis?

A

The Formation of Blood Cells

26
Q

Where is the site of Hematopoeisis?

A

The red bone marrow which contains Pluripotent stem cells ( cells that have the capacity to develop into many different types of cells)

27
Q

Depending on the signal that is picked up by the receptors on the pluripotent stem cells (located in red bone marrow) Pluripotent cells generate either ______ or _______?

A

Myloid Stem Cells or Lymphoid Stem Cells

28
Q

What Hormone stimulates the Formation of RBC’s?

A

EPO (Erythropoeitin)

29
Q

What is a major stimulus for extra production of EPO

A

Hypoxia (inadequate oxygen levels)

30
Q

Name and explain the three mechanisms that reduce blood loss?

A
  1. Vascular Spasms: when arteries or arterioles are damaged their smooth muscle contract (vasoconstriction).