Blood Cells

Question 1

What are the peripheral blood counts for 
Hb 
RBC 
WBC
Platelets

Answer 1

Hb 130-160 g/l
RBC 4.4-5.5
WBC 7-11
Platelets 150-400

Question 2

What are the 5 main functions of red cells

Answer 2

Delivery oxygen 
Carry haemoglobin 
Maintain haemoglobin in ferrous state 
Maintain osmotic equilibrium 
Generate energy (ATP)

Question 3

What are the two main RBC metabolism pathways

Answer 3

Embdem Meyerhof

• glucose into lactate
• ATP generated

Heroes monophosphate pathway

• glucose-6-phosphate metabolised
• generates NADPH

Question 4

What are the four stages of erythropoiesis

Answer 4

Kidney senses hypoxia and increases erythropoietin production
Erythropoietin acts on bone marrow
Kidney senses increased oxygen
Kidney decreases erythropoietin production

Question 5

What is the structure and function on platelets

Answer 5

Structure

• membrane - phopholipid surface for clotting factor
• dense bodies - 5HT ADP and Ca for platelet aggregation

Function
- adhere via vWF to form plug

Involved in clotting cascade and fibrin mesh traps platelets and red cells