BLOOD BANKING Flashcards
The following microorganisms implicated in TTBI that is typically associated with RBC products:
1. Pseudomonas aeruginosa
2. Staphylococcus aureus
3. Serratia marcescens
4. Staphylococcus lugdunensis
1 & 3
Characterized by a (+) DAT 24 hours to 28 days after transfusion with a
positive alloantibody in patient’s plasma and evidence of hemolysis;
A. FHTR
B. FNHTR
C. DHTR
D. DSTR
C. DHTR
Characterized by accelerated destruction of transfused RBC due to antibody-mediated incompatibility. Occurs during or within 24 hours of transfusion:
A. AHTR
B. ANHTR
C. DHTR
D. FHTR
A. AHTR
It occurs 5-10 days after transfusion due to alloimmunization to platelet specific antibodies from prior transfusion or pregnancy:
A. DHTR
B. TA- GVHD
C. TTBI
D. PTP
D. PTP
What would be the result of group A blood given to a group O patent?
A. Non-immune Transfusion Reaction
B. Delayed Hemolytic Transfusion Reaction
C. Immediate Hemolytic Transfusion Reaction
D. Febrile Non-Hemolytic Transfusion Reaction
C. Immediate Hemolytic Transfusion Reaction
Irradiation of blood is performed to prevent
A. Febrile nonhemolytic transfusion reaction
B. Transfusion-associated graft-versus-host disease
C. Delayed hemolytic transfusion reaction
D. Transfusion-associated circulatory overload
B. Transfusion-associated graft-versus-host disease
A patient has a hemolytic reaction to blood transfused 8 days ago. What is the most likely cause?
A. Immediate, non immunologic, probably as a result of volume overload
B. Delayed, Immunologic, probably as a result of an antibody such as anti-Jka
C. Delayed non immunologic, probably as a result of iron overload
D. Immediate, immunologic probably because of clerical error, ABO incompatibility
B. Delayed, Immunologic, probably as a result of an antibody such as anti-Jka
Which type of transfusion reaction occurs in about 1% of all transfusions, results in temperature-rise of greater than 1C above 37C associated with blood component transfusion, and is not related to the patient’s medical
condition?
A. Immediate hemolytic
B. Delayed hemolytic
C. Febrile non-hemolytic
D. TRALI
C. Febrile non-hemolytic
In the event of adverse during transfusion reaction, what must be done first?
A. Finish the transfusion first, prefuse the IV line with warm saline
B. Check for the patient’s body temperature & blood pressure
C. Stop the transfusion at once, call the attending physician
D. Do an antibody screen/panel work up
C. Stop the transfusion at once, call the attending physician
Adverse reaction mimics AHTR, TRALI, TACO & TBBI
A. ATR
B. FNHTR
C. TAD
D. TA-GVHD
B. FNHTR
An acute respiratory distress from pulmonary edema is generated by intravascular volume owing to excessive transfused fluid or too fast infusion resulting in adverse reaction:
A. Hypotensive TR
B. TACO
C. TAD
D. TRALI
B. TACO
To prevent this adverse transfusion reaction, patients must be given an irradiated blood component
A. ATR
B. FNHTR
C. TAD
D. TA-GVHD
D. TA-GVHD
The following microorganisms implicated in TTBI that is typically associated with RBC products:
1. Pseudomonas aeruginosa
2. Staphylococcus aureus
3. Serratia marcescens
4. Staphylococcus lugdunensis
D. 2 & 4
What components(g) may be shipped together with FFP?
A. Frozen RBCs and cryoprecipitate
B. Platelets
C. Packed RBCs and granulocytes
D. Double red cell
A. Frozen RBCs and cryoprecipitate
Which component has the longest expiration date?
A. Cryoprecipitate
B. FFP
C. Frozen RBCs
D. Platelet concentrates
C. Frozen RBCs
What components) is (are) indicated for patients who have anti-IgA
antibodies?
A. Whole blood
B. Packed RBCs
C. Washed or deglycerolized RBCS
D. Granulocytes
C. Washed or deglycerolized RBCS
How many day/s a rejuvenated solution can still be used?
A. 1 day
B. 3 days
C. 35 days
D. 42 days
B. 3 days
FDA and AABB recommend a minimum dose of gamma irradiation of to the central portion of the blood unit with no less than delivered to any part of the blood unit
A. 25 Gy and 15 Gy
B. 20 Gy and 16 Gy
C. 23 Gy and 14 Gy
D. Any of the choices.
A. 25 Gy and 15 Gy
What is the correct order of saline conc. used in deglycerolization?
A. 1.6%, 12%, 0.2%
B. 12%, 1.6%, 0 2%
C. 0.2%, 12%, 1.6%
D. 12%, 1.6%, 0.9%
D. 12%, 1.6%, 0.9%
What is the correct order of preparing a blood component from the primary bag?
A. Weigh- balance- centrifuge- express
B. Weigh- centrifuge- express-balance
C. Balance-weigh-express-centrifuge
D. Centrifuge-weigh-balance-express
A. Weigh- balance- centrifuge- express
The blood bags and tubes are usually made out of:
A. PVC
B. Glycerol
C. HES
D. Aluminum
A. PVC
Which among the ff. describes a COLLOID?
1. Easily excreted
2. Expensive
3. Example is Dextran
A. 1 only
B. 1 and2
C. 2 and 3
D. 1 and 3
C. 2 and 3
Which of the following lists the correct shelf life for the component?
A. Deglycerolized RBCs–24 hours
B. RBCs (CPD)–35 days
C. Platelet concentrate–10 days
D. FFP–10 years
A. Deglycerolized RBCs–24 hours
With the spin condition of 5,000 x g, 5 minutes, what components can you prepare from a primary bag?
1. PRBC
2. Cryoprecipitate
3. PRP
1 and 3
2 Concentrate of plasma gamma globulins in an aqueous solution:
A. Immune Serum Globulin
B. Normal Serum Albumin
C. Prothrombin Complex Concentrates
D. Recombinant FXIlI
A. Immune Serum Globulin
Washed Red Cells must be transfused
A. Within 4 Hours
B. Within 6 Hours
C. Within 24 Hours
D. Within 35 days
C. Within 24 Hours
Once thawed, a cryoprecipitate pooled in the transfusion service laboratory using an open system must be transfused:
A. Within 4 Hours
B. Within 6 Hours
C. Within 24 Hours
D. Within 72
A. Within 4 Hours
A unit of granulocyte concentrates must contain
A. ≥ 1.0 x 10^8 Granulocytes
B. ≥ 8.3 x 10^5 Granulocytes
C. ≥ 1.0 x 10^10 Granulocytes
D. ≥ 8.3 x 10^18 Granulocytes
C. ≥ 1.0 x 10^10 Granulocytes
Platelet from apheresis donation or a single donor platelet must contain:
A. At least 3 x 10^18 Platelets
B. At least 3 x 10^11 Platelets
C. At least 5.5 x 10^18 Platelets
D. At least 5.5 x 10^11 Platelets
B. At least 3 x 10^11 Platelets
Leukoreduced whole blood component must contain how many residual WBCs:
A. < 5.0 x 10^6
B. < 5.0 x 10^2
C. < 5.10 x 10^2
D. < 8.3 x 10^8
A. < 5.0 x 10^6
Red blood cell blood component with CPD-A-AS-3 as is anticoagulant preservative has a shell life of
A. 21 Days
B. 35 Days
C. 42 Days
D. 45 Days
C. 42 Days
What is the expected shelf life of the CPDA1 Whole blood with spit pilot tube?
A. 24 hours
B. 21 days
C. 35 days
D. 42 days
A. 24 hours
If the Packed RBC with CPDA1 was prepared last April 2, 2023. The blood must be kept until.
A. May 7, 2023
B. April 29,2023
C. May 14, 2023
D. May 8, 2023
A. May 7, 2023
All of the following are true regarding washed RBCs, except:
A. RBCs are washed with 1-2 L of normal saline
B. Volume 1s 180 mL
C. Shelf life is extended
D. The leukocytes are removed
C. Shelf life is extended
Type of transfusion reaction indicated as the most severe and maybe life
threatening due to ABO incompatibility
A. Immediate Hemolytic
B. Immediate non hemolytic
C. Delayed hemolytic
D. Delayed non hemolytic
A. Immediate Hemolytic
Which of the following pathogens is commonly cultured on blood bags
stored at room temperature?
A. Staphylococcus aureus
B. Bacillus subtilis
C. Yersinia enterocolitica
D. Eschericia coli
A. Staphylococcus aureus
Which of the following is incorrect regarding platelet concentrate special considerations?
A. pH should be > 6.2
B. with continuous agitation
C. Stored at 1-6℃
D. Expiration of 5 days if closed system
C. Stored at 1-6℃
It is associated with increase of 1℃ with no apparent reason aside from
blood donation
A. TA-GVHD
B. TRALI
C. FNHTR
D. TACO
C. FNHTR
What is the storage temperature of Packed RBC?
A. 18℃
B.1-6℃
C. 20-24℃
D. -18℃
B.1-6℃
Whole blood which is an open system has an expiration of 24hrs. Other components such as platelets in that whole blood can be used because these are considered as close system
A. 1st statement is true
B. 2nd statement is true
C. Both statements are true
D. None of the statements are true
A. 1st statement is true
FOR QUESTIONS 41-44: Refer to the case study below:
A 35-year-old man has been planning to have an autologous donation due to the scarcity of blood unit specific with his blood type, yet he wants the blood to be processed and kept in the BB just in case he will need it.
What is the component that the medtech should prepare?
A. Cryoprecipitate
B. Platelet concentrate
C. Leukoreduced RBC
D. FFP
E - For rare phenotypes frozen deglycerolized RBC
What will be the best agent/anticoagulant to be used to prolong the RBC
shelf life most especially for long-term storage?
A. NSS
B. HES
C. Glycerol
D. Cobalt 60
C. Glycerol
When will be the maximum expected shelf life of the component prepared by the MT?
A. 35 days
B. 42 days
C. 1 year
D. 5 years
E
What is the temperature storage of the component being prepared?
A. 20-24degC
B. 1-6degC
C. -18degC
D. -65degC
D. -65degC
FOR QUESTIONS 45-46: Refer to the case study below:
A cancer patient recently developed a severe infection. The patient’s
hemoglobin is 6 g/dL owing to chemotherapy with a drug known to cause
bone marrow depression, immunodeficieny, and immunosupression.
Which blood products are indicated for this patient?
A. Liquid plasma and cryoprecipitate products
B. Crossmatched platelets and washed RBCs
C. Factor IX concentrates and FFP
D. Irradiated products
D. Irradiated products
How will the component “Answer in #45” be prepared?
A. Blood is treated with gamma ray device to prevent the proliferation of visible T lymphocyte
B. Plasma immunoglobulins is first frozen and then it is slowly thawed
C. T lymphocytes are harvested by doing a hard spin from a whole blood
D. Obtained from pools of viable plasma lymphocytes and coagulation factors, frozen, then thawed
A. Blood is treated with gamma ray device to prevent the proliferation of visible T lymphocyte
Expiry of washed RBC with CPDA-1 an additive
A. 35 days
B. 21 days
C. 42 days
D. 24hrs
D. 24hrs
How many percent of hematoont is expected to increase per blood bag
unit specifically the pRBCs?
A. 1-1.5%
B. 3%
C. 6-10%
D. 15-30%
B. 3%
All of the following packed RBC could be given, except
A. Rapidly bleeding patent
B. Cardiac Failure
C. Hemorrhagic Shock
D. TA-GHD
D. TA-GHD
Clerical error is the most indicated of transfusion related problems
encountered on hospitals:
A. TRUE
B. FALSE
A. TRUE
Using the CPD (Citrate Phosphate Dextrose), what is the allowable shelf
life for blood for transfusion therapy?
A. 21 days
B. 35 days
C. 42 days
D. Not an approved anticoagulant
A. 21 days
CPD-A1 PRBC if collected in a closed system can be transfused up to:
A. 21 days
B. 35 days
C. 42 days
D. Not an approved anticoagulant
B. 35 days
The most common anticoagulant used for apheresis procedures is.
A. Heparin
B. Sodium fluoride
C. Warfarin
D. Citrate
D. Citrate
Autologous donation can be best done for the following individual/s:
A. Donor with Bombay Phenotype
B. Any person regardless of blood type
C. Both A and B
D. Neither A nor B
C. Both A and B
Apheresis procedure indicated for patient/s with thalassemia syndrome:
A. Leukapheresis
B. Lymphocytapheresis
C. Erythrocytapheresis
D. Neocytapheresis
D. Neocytapheresis
The apheresis procedure for patients with Acute myelogenous leukemia (AML):
A. Leukapheresis
B. Lymphocytapheresis
C. Erythrocytapheresis
D. Neocytapheresis
A. Leukapheresis
This component is prepared when only oxygen carrying capacity is needed, not necessarily volume expansion.
A. Whole blood
B. Packed RBCs
C. HES
D. Plasma exchange
B. Packed RBCs
This pheresis procedure is done to remove the offending agent in the
plasma causing clinical symptoms in cases of Paraproteinemia.
A. Lymphocytapheresis
B. Monocytapheresis
C. Plasma exchange
D. Neocytapheresis
C. Plasma exchange
This centrifugation method in apheresis requires double arms and needles
A. Intermittent flow
B. Batch flow
C. Continuous flow
D. Maximum for
C. Continuous flow
This is a sedimenting agent used in this apheresis procedure granulocyte collection which causes red cells to form rouleaux.
A. HES
B. Corticosteroids
C. Citrate
D. Glycerol
A. HES
