Blood Bank Overview

Question 1

Autologous donation

Answer 1

donor for own use

Question 2

Allogenic donation

Answer 2

donor for someone else

Question 3

Zeta potential

Answer 3

force of repulsion between RBCs

Question 3

Apheresis

Answer 3

whole blood is removed and returned all but the product needed back to donor

Question 4

Locus

Answer 4

location of a particular gene

Question 4

Gene

Answer 4

specific sequence of nucleotides occupying a specific location on a chromosome

Question 5

Allele

Answer 5

two or more different genes that occupy a specific location

Question 6

Homozygous

Answer 6

identical genes AA

Question 7

Heterozygous

Answer 7

having different alleles at a given gene locus AB

Question 8

Dominant

Answer 8

trait or characteristic that will be expressed in the offspring

Question 9

Recessive

Answer 9

trait that does not express itself in the presence of a dominant allele

Question 10

Codominant

Answer 10

both alleles expressed

Question 11

Amorph

Answer 11

lack of expression

Question 12

Cis

Answer 12

genes found on same chromosome

Question 13

Trans

Answer 13

genes found on opposite chromosome

Question 14

Genotype

Answer 14

what is actually on gene (AO)

Question 15

Phenotype

Answer 15

the observable expression of trait (A)

Question 16

Dosage

Answer 16

when there is more antigen expressed with homozygous alleles than heterozygous

Question 17

Kernicterus

Answer 17

toxic levels of bilirubin that causes brain damage

Question 18

How long is CPD good for

Answer 18

21 days

Question 19

How long is CPDA1 good for

Answer 19

35 days

Question 20

How long is blood with additives good for

Answer 20

42 days

Question 21

How long is irradiated blood good for

Answer 21

28 days or original expiration whichever comes first

Question 22

Where are blood products produced

Answer 22

Bone marrow

Question 23

What is the purpose of blood

Answer 23

Transport oxygen and CO2

Question 24

What state must iron be in to be functional

Answer 24

ferrous state

Question 25

Where are antigens found in BB

Answer 25

surface of RBCs

Question 26

Where are antibodies found in BB

Answer 26

plasma/serum

Question 27

Transfusions are indicated when

Answer 27

decreased RBC count, low hemoglobin

Question 28

Packed RBCs are used for

Answer 28

Treat anemia, less to infuse, increased O2 transport

Question 29

FFP (fresh frozen plasma) used for

Answer 29

provides all coagulation factors

Question 30

Cryoprecipitate used for

Answer 30

provides factors VIII, XIII, Von Wilebrand factor, fibrinogen, and fibrinonectin

Question 31

What is included in blood donor exam

Answer 31

110 lbs or more, temperature cannot exceed 99.5/37.5, pulse 50-100 BPM, blood pressure not over 180/100, hemoglobin 11(w) 12.5 (m), hematocrite >38 (allogenic) >33 autologous

Question 32

Temporary deferral

Answer 32

risk to potential recipient for limited amount of time

Question 33

Permanent deferral

Answer 33

condition or exposure that causes them to never be eligible to donate

Question 34

Indefinite deferral

Answer 34

unable to give blood for unspecified amount of time

Question 35

Autologous hematocrit and hemoglobin

Answer 35

hematocrit 33% hemoglobin 11 g/dL

Question 36

Directed donation

Answer 36

donations made to be used by a specific person

Question 37

Therapeutic phlebotomy

Answer 37

draw blood from patient to decrease RBC count and hematocrit

Question 38

Tests on donor blood at the donor facility

Answer 38

ABO forward, ABO reverse, Rh - weak D if Rh negative, antibody screen, infectious diseases

Question 39

Tests on donor blood at the transfusing facility

Answer 39

ABO forward, Rh if Rh negative

Question 40

Storage, transport, and frozen temperature for PRBC

Answer 40

Storage 1-6 C Transport 1-10C Frozen -65--85C

Question 41

Storage temperature for cryoprecipitate

Answer 41

- 18 C

Question 42

Storage temps for FFP

Answer 42

-18 C

Question 43

Storage temperature for platelets

Answer 43

20-24 C

Question 44

Storage temperature for FFP

Answer 44

1-6C

Question 45

Storage temperature for thawed cryoprecipitate

Answer 45

1-6C

Question 46

Transfusing 1 unit of PRBCs should increase hemoglobin/hematocrit by how much

Answer 46

hemoglobin 1 g/dL hematocrit 3%

Question 47

LEukocyte poor blood

Answer 47

removes WBCs, prevent febrile reactions, CMV transmission

Question 48

Irradiated blood

Answer 48

exposing blood to gamma or x ray inactivate T lymphs, expiration 28 days or original expiration date

Question 49

Basis of BB reactions

Answer 49

antigens and antibodies

Question 50

Sensitization

Answer 50

initial binding of antibody with antigen, when two come together to form immune complex

Question 51

Lattice formation

Answer 51

second step of agglutination, connect all together

Question 52

LISS

Answer 52

to decrease ionic strength

Question 53

Over centrifugation

Answer 53

false pos

Question 54

Under centrifugation

Answer 54

false neg

Question 55

Prozone

Answer 55

too many antibodies/ false negative

Question 56

Postzone

Answer 56

too many antigens/ false negative