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Blood Bank > Blood Bank Overview > Flashcards

Blood Bank Overview Flashcards

1
Q

Autologous donation

A

donor for own use

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2
Q

Allogenic donation

A

donor for someone else

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3
Q

Zeta potential

A

force of repulsion between RBCs

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3
Q

Apheresis

A

whole blood is removed and returned all but the product needed back to donor

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4
Q

Locus

A

location of a particular gene

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4
Q

Gene

A

specific sequence of nucleotides occupying a specific location on a chromosome

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5
Q

Allele

A

two or more different genes that occupy a specific location

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6
Q

Homozygous

A

identical genes AA

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7
Q

Heterozygous

A

having different alleles at a given gene locus AB

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8
Q

Dominant

A

trait or characteristic that will be expressed in the offspring

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9
Q

Recessive

A

trait that does not express itself in the presence of a dominant allele

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10
Q

Codominant

A

both alleles expressed

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11
Q

Amorph

A

lack of expression

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12
Q

Cis

A

genes found on same chromosome

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13
Q

Trans

A

genes found on opposite chromosome

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14
Q

Genotype

A

what is actually on gene (AO)

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15
Q

Phenotype

A

the observable expression of trait (A)

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16
Q

Dosage

A

when there is more antigen expressed with homozygous alleles than heterozygous

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17
Q

Kernicterus

A

toxic levels of bilirubin that causes brain damage

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18
Q

How long is CPD good for

A

21 days

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19
Q

How long is CPDA1 good for

A

35 days

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20
Q

How long is blood with additives good for

A

42 days

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21
Q

How long is irradiated blood good for

A

28 days or original expiration whichever comes first

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22
Q

Where are blood products produced

A

Bone marrow

23
Q

What is the purpose of blood

A

Transport oxygen and CO2

24
Q

What state must iron be in to be functional

A

ferrous state

25
Q

Where are antigens found in BB

A

surface of RBCs

26
Q

Where are antibodies found in BB

A

plasma/serum

27
Q

Transfusions are indicated when

A

decreased RBC count, low hemoglobin

28
Q

Packed RBCs are used for

A

Treat anemia, less to infuse, increased O2 transport

29
Q

FFP (fresh frozen plasma) used for

A

provides all coagulation factors

30
Q

Cryoprecipitate used for

A

provides factors VIII, XIII, Von Wilebrand factor, fibrinogen, and fibrinonectin

31
Q

What is included in blood donor exam

A

110 lbs or more, temperature cannot exceed 99.5/37.5, pulse 50-100 BPM, blood pressure not over 180/100, hemoglobin 11(w) 12.5 (m), hematocrite >38 (allogenic) >33 autologous

32
Q

Temporary deferral

A

risk to potential recipient for limited amount of time

33
Q

Permanent deferral

A

condition or exposure that causes them to never be eligible to donate

34
Q

Indefinite deferral

A

unable to give blood for unspecified amount of time

35
Q

Autologous hematocrit and hemoglobin

A

hematocrit 33%
hemoglobin 11 g/dL

36
Q

Directed donation

A

donations made to be used by a specific person

37
Q

Therapeutic phlebotomy

A

draw blood from patient to decrease RBC count and hematocrit

38
Q

Tests on donor blood at the donor facility

A

ABO forward, ABO reverse, Rh - weak D if Rh negative, antibody screen, infectious diseases

39
Q

Tests on donor blood at the transfusing facility

A

ABO forward, Rh if Rh negative

40
Q

Storage, transport, and frozen temperature for PRBC

A

Storage 1-6 C
Transport 1-10C
Frozen -65–85C

41
Q

Storage temperature for cryoprecipitate

A
  • 18 C
42
Q

Storage temps for FFP

A

-18 C

43
Q

Storage temperature for platelets

A

20-24 C

44
Q

Storage temperature for FFP

A

1-6C

45
Q

Storage temperature for thawed cryoprecipitate

A

1-6C

46
Q

Transfusing 1 unit of PRBCs should increase hemoglobin/hematocrit by how much

A

hemoglobin 1 g/dL
hematocrit 3%

47
Q

LEukocyte poor blood

A

removes WBCs, prevent febrile reactions, CMV transmission

48
Q

Irradiated blood

A

exposing blood to gamma or x ray inactivate T lymphs, expiration 28 days or original expiration date

49
Q

Basis of BB reactions

A

antigens and antibodies

50
Q

Sensitization

A

initial binding of antibody with antigen, when two come together to form immune complex

51
Q

Lattice formation

A

second step of agglutination, connect all together

52
Q

LISS

A

to decrease ionic strength

53
Q

Over centrifugation

A

false pos

54
Q

Under centrifugation

A

false neg

55
Q

Prozone

A

too many antibodies/ false negative

56
Q

Postzone

A

too many antigens/ false negative

57
Q
A

Blood Bank (1 decks)

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