Blood and hematopoiesis

Question 1

Plasma %

Answer 1

55% of whole blood

Question 2

Erythrocytes %

Answer 2

44% of whole blood

Question 3

Buffy coat

Answer 3

Leukocytes and platelets ; <1% of whole blood

Question 4

Water content of plasma

Answer 4

92%

Question 5

Plasma proteins

Answer 5

7% of plasma

Question 6

Solute content of plasma

Answer 6

<1%

Question 7

Albumin functions

Answer 7

Maintain osmotic pressure in capillaries; contribute to blood viscosity; transports fatty acids, electrolytes, hormones, and drugs

Question 8

Alpha globulin func

Answer 8

Transports lipids and metal ions

Question 9

Beta globulin function

Answer 9

Transports iron ions and lipids in bloodstream

Question 10

Gamma globulin function

Answer 10

Antibodies :)

Question 11

Fibrinogen

Answer 11

Blood clotting; precursor of fibrin

Question 12

Zone of Pallor

Answer 12

1/3 of RBC center

Question 13

Lifespan of RBC

Answer 13

120 days

Question 14

Normal values for platelets

Answer 14

150,000-400,000 mm^3

Question 15

Lifespan of platelets

Answer 15

10 days

Question 16

Hyalomere

Answer 16

Lightly stained peripheral zone

Question 17

Granulomere

Answer 17

Darkly stained central zone

Question 18

Contents of delta granules

Answer 18

ATP, ADP, serotonin

Question 19

Contents of alpha granules

Answer 19

Platelet derived growth factor, platelet factor 4, platelet specific proteins

Question 20

Site of RBC breakdown

Answer 20

Liver, spleen, bone marrow

Question 21

Carbaminohemoglobin

Answer 21

HgB with CO2

Question 22

Carboxyhemoglobin

Answer 22

Hgb with CO

Question 23

Normal values of leukocytes

Answer 23

4,500-11,000/mm^3

Question 24

% of Neutrophils

Answer 24

50-70%

Question 25

% of Lymphocytes

Answer 25

20-40%

Question 26

% of Monocytes

Answer 26

2-8%

Question 27

% of Eosinophils

Answer 27

1-4%

Question 28

% of Basophils

Answer 28

0.5-1%

Question 29

Drumstick-like appendage on neutrophils

Answer 29

Barr-body

Question 30

Myeloperoxidase

Answer 30

Generates hypochlorite and other substance against bacteria

Question 31

Lysozyme

Answer 31

Degrades bacterial cell walls

Question 32

Defensins

Answer 32

Cysteine-rich proteins that bind and disrupt cell membranes

Question 33

Neutrophils

Answer 33

Weakly staining granules

Question 34

Eosinophils

Answer 34

Golden-red staining

Question 35

Basophils

Answer 35

Dark purple staining granules

Question 36

Bands

Answer 36

Immature neutrophils with horse-shoe shaped nucleus

Question 37

3-5 lobed leukocyte

Answer 37

Neutrophil

Question 38

Bilobed leukocyte

Answer 38

Eosinophil

Question 39

S-shaped bilobed

Answer 39

Basophils

Question 40

Open canalicular system of vesicles

Answer 40

Uptake of factors from plasma

Question 41

Dense tubular system of irregular tubular vesicles

Answer 41

Rapid degranulation; exocytosis of proteins

Question 42

Cytokines

Answer 42

Trigger loosening of intercellular junctions

Question 43

P-selectin

Answer 43

Cell adhesion proteins on endothelial luminal surface; exocytosed from weibel-palade bodies

Question 44

erythroid progenitor cell

Answer 44

Proerythroblast

Question 45

sequence of erythropoiesis

Answer 45

proerythroblast -> basophilic erythroblast -> polychromatophilic erythroblast -> orthochromatophilic eryth -> reticulocyte -> erythrocyte

Question 46

stage when pyknotic nucleus is ejected

Answer 46

orthochromatophilic erythroblast

Question 47

normoblast

Answer 47

orthochromatophilic erythroblast

Question 48

sequence of granulopoiesis

Answer 48

progenitor cell (CFU-G) -> myeloblast -> protomyelocyte -> myelocyte -> metamyelocyte -> mature granulocyte

Question 49

4 compartments of neutrophils

Answer 49

granulopoietic compartment, storage compartment, circulating compartment- marginating compartment

Question 50

sequence of thrombopoiesis

Answer 50

megakaryoblast -> megakaryocyte with proplatelet extensions -> platelet