blood and blood film Flashcards
which cells are derived from lymphoid stem cells
- b cells
- t cells
- natural killer cells
which cells are derived from myeloblasts
granulocytes
- basophils
- neutrophils
- eosinophils
- monocytes -> macrophages
which cells are platelets derived from
megakaryocytes
from myeloid stem cells
which cells are RBCs derived from
erythrocytes
from myeloid stem cells
lifespan of RBC
3 months
lifespan of platelets
10 days
where do lymphocytes mature
- T cells in thymus gland
- B cells in bone marrow
in which condition are target cells seen on blood film
iron deficiency anaemia
post-splenectomy
in which condition are heinz bodies seen on blood film
G6PD
alpha-thalassaemia
in which condition are reticulocytes seen on blood film
haemolytic anaemia
-> conditions with rapid turnover of RBC as reticulocytes are immature RBCs
what are schistocytes
fragments of red blood cells indicating physical damage to them
in which conditions are schistocytes seen on blood film
haemolytic uraemic syndrome
DIC
thrombotic thrombocytopaenia purpura
in which condition are smudge cells seen on blood film
chronic lymphocytic leukaemia (CLL)
in which condition are spherocytes seen on blood film
autoimmune haemolytic anaemia
hereditary spherocytosis