blood and blood film Flashcards

1
Q

which cells are derived from lymphoid stem cells

A
  • b cells
  • t cells
  • natural killer cells
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2
Q

which cells are derived from myeloblasts

A

granulocytes

  • basophils
  • neutrophils
  • eosinophils
  • monocytes -> macrophages
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3
Q

which cells are platelets derived from

A

megakaryocytes

from myeloid stem cells

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4
Q

which cells are RBCs derived from

A

erythrocytes

from myeloid stem cells

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5
Q

lifespan of RBC

A

3 months

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6
Q

lifespan of platelets

A

10 days

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7
Q

where do lymphocytes mature

A
  • T cells in thymus gland

- B cells in bone marrow

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8
Q

in which condition are target cells seen on blood film

A

iron deficiency anaemia

post-splenectomy

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9
Q

in which condition are heinz bodies seen on blood film

A

G6PD

alpha-thalassaemia

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10
Q

in which condition are reticulocytes seen on blood film

A

haemolytic anaemia

-> conditions with rapid turnover of RBC as reticulocytes are immature RBCs

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11
Q

what are schistocytes

A

fragments of red blood cells indicating physical damage to them

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12
Q

in which conditions are schistocytes seen on blood film

A

haemolytic uraemic syndrome
DIC
thrombotic thrombocytopaenia purpura

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13
Q

in which condition are smudge cells seen on blood film

A

chronic lymphocytic leukaemia (CLL)

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14
Q

in which condition are spherocytes seen on blood film

A

autoimmune haemolytic anaemia

hereditary spherocytosis

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