Blood Administration Flashcards
Benefits to Blood management
- Improves patient outcomes
- Lessens exposure to infection
- Facilitates faster recovery
- Decreases post operative infection rates
Blood transfusion is?
the replacement of blood or blood components when O2 delivered to the tissue is compromised.
blood and blood products are used to?
- Improve or restore oxygen carrying capacity & tissue oxygenation
- Restore blood volume lost d/t trauma, haemorrhage, surgery, and burns etc.
- Correct red blood cell deficiency
- Maintain or improve blood’s clotting ability
Components of whole blood:
- Concentrated Red Cells
- White cells
- Plasma (proteins, globulins, albumin)
- Platelets
Non Fractionated Blood Products
- Red Blood Cells
- Fresh Frozen Plasma
- Platelets
- Cryoprecipitate
- Autologous Whole Blood- where the PTs whole blood is injected into places to help healing/clotting
Fractionated Blood Products
- Immune Globulin- antibodies Y
- Albumin- in blood plasma. Proteins that reg blood vol
- Factor Concentrations- clotting factors
Albumin
> Red Blood Cells
> Fresh Frozen Plasma- fluid portion of blood. Contains components of : coagulating factors, oncotic pressure and modulate immunity
> Platelets- stop bleeding
> Cryoprecipitate- frozen blod product prepared from plasma. clotting factors
> Autologous Whole Blood- process where PTs own blood is injected into an area of the body for the purpose of healing
Pentaspan
- plasma expander
- synthetic cornstarch derivative in saline solution
- no risk of disease transmission
- 1.5 x greater vol expander than albumin with longer duration of expansion
blood group O
is a universal donor
blood group AB
is a universal recipient
Rh factor
> antigen D is an inherited antigen in the surface of RBCs
ppl with antigen D are Rh+
ppl without are Rh -
exposure to antigen D is necessary for production of Rh antibodies
If the reciepient blood cell antigen is not compatible with the donor cell antigen,
a reaction called agglutinin (antibody)
> antibodies destroy or neutrilize antigens by clumping (agglutination) YYYyyYyY
Massive blood transfusions
> PRBCs are deficient in clotting factors & platelets
> Calcium binds with preservatives in PRBCs
> For these reasons, FFP, platelets, calcium and cryoprecipitate are given to patients receiving massive blood transfusions.
> Rule of thumb – for every three units of PRBCs the patient is given 1 FFP and 1 bag of platelets
General rule of thumb for blood and blood prod admin
> Written consent is required to administer non-fractionated blood products (2 nurses needed to check)
> RN, RPN, Physician & LPN may check fractionated blood products without a second person.
> No Medication may be added to the blood or infused through the same tubing.
Transfusion reactions:
A systemic response to the administration of a blood product that is either incompatible with that of the recipient, contains allergens to which the recipient is sensitive or is contaminated with bacteria
Most common occurance of transfusion reaction is d/t:
- admin errors. incompatible blood
2. misidentification
Types of blood transfusion reactions
- Acute hemolytic - chills, rigors, dyspnoea, chest and/or flank pain, discomfort at infusion site, sense of dread, abnormal bleeding
- Febrile, non hemolytic (most common) > 38 degress or 1 degree above baseline. Chills, rigors, increased respiratory rate, change in blood pressure, anxiety and a headache
- Mild allergic- hives (urticarial), upper resp, N/V, abd pain
- Anaphylactic- sudden onset of severe hypotension, cough, bronchospasm (respiratory distress and wheezing), laryngospasm, angioedema, urticaria, nausea, abdominal cramps, vomiting, diarrhoea, shock and loss of consciousness. This may be a fatal reaction.
- Circulatory Overload- dyspnoea, orthopnea(SOB lying flat), cyanosis, tachycardia, increased blood pressure and pulmonary edema
- Sepsis- high fever, rigors (shiver), hypotension, tachycardia, N/V,
Know your signs and symptoms associated with each type of transfusion reaction!!