Blood

Question 1

Most common inherited bleeding disorder?

Answer 1

vWD

Question 2

treatment for methemoglobinemia

Answer 2

methylene blue

methylthioninium chloride

Question 3

underlying problem in methemoglobinemia

Answer 3

oxidation of Fe2+ to Fe 3+

(ferrous to ferric) , cannot release O2 to tissue, left shift

Question 4

Ciaplatin cause which electrolyte disturbance

Answer 4

hypomagnesemia

Question 5

what to look for in white cell in leukemoid reaction

Answer 5

toxic granulation (Dohle bodies)

Question 6

Lead poisoning, which urine test abnormal

Answer 6

elevated coproporphyrin

Question 7

Acute intermittent porphyria, which urine test abnormal

Answer 7

elevated porphobilinogen

Question 8

cut off to to give steroid for ITP

Answer 8

30*10^9/L

Question 9

most common inherited thrombophilia

Answer 9

factor V leiden

Question 10

what do you see in blood film of celiac patients

Answer 10

target cell and Howell-Jolly bodies

Question 11

most common clinically significant primary immunodeficiency

Answer 11

CVID

Question 12

breast cancer tumor marker

Answer 12

153

Question 13

ovarian cancer tumor marker

Answer 13

125

Question 14

bombesin, which tumor

Answer 14

small cell lung cancer gastric cancer, neuroblastoma

Question 15

prevalence of factor V leiden (heterozygous)

Answer 15

5%

Question 16

fastest conduction in the heart

Answer 16

Purkinje fibres

Question 17

treatment for homocystinuria

Answer 17

vitamin B6 (pyridoxine)

Question 18

which hormone only secreted by adrenal medulla

Answer 18

adrenaline(epi)

Question 19

most common cardiac defect in Turner’s syndrome

Answer 19

Bicuspid aortic valve

Question 20

most common renal abnormality in Turner’s syndrome

Answer 20

horseshoe kidney