Blood Flashcards
What are the main functions of blood?
- Carriage of biologically active material and gases.
- Clotting
- Defence
- Maintenance of ECF pH
- Thermoregulation
What are the three types of plasma proteins?
- Albumin
- Globulin
- Fibrinogen and clotting factors
What is meant by colloidal oncotic pressure?
This is the ‘pull’ created by plasma proteins. It pulls water across the endothelial cells of the capillary wall. Sodium can follow, long with other penetrating components of the ISF.
What can Red Blood Cells also be called?
Erythrocytes
Describe the structure of erythrocytes.
Biconcave disk shape, without a nucleus. This allows more space for haemoglobin.
What is erythropoiesis?
This is the development of erythrocytes from pluripotent stem cells, accelerated by erythropoietin.
What is the most abundant blood cell?
Erythrocyte
Describe the structure of platelets.
Cell fragments
Megakaryocyte cytoplasm wrapped up in megakaryocyte membrane. No nucleus
What are the three types of granulocytes?
Eosinophils
Neutrophils
Basophils
What do monocyte cells mature into?
Macrophages
What is the function of macrophages?
To engulf and destroy pathogens in phagocytosis
What is the function of neutrophils?
- Phagocytosis
- To trap pathogens in NETs (Neutrophil extracellular traps)
What is the function of eosinophils?
To attack pathogens which are too large for neutrophils and other defensive cells
In what scenario is eosinophil count extremely elevated?
During an allergic reaction
What is the function of basophils?
To release histamine and heparin to stimulate inflammation