Blood Flashcards
If your blood agglutinates with anti-B sera and anti-D sera, but not with anti-A, what blood type do you have?
B+
What WBC would you expect to be elevated if you are allergic to something? Why?
Eosinophils b/c they move to the area and release a variety of toxins
Describe Neutrophils
Round cell, multi-lobed nucleus, granules in cytoplasm, phagocytes
Describe Leukocytes
WBCs, move in and out of blood vessels, Neutrophils are the most common
Describe Eosinphils
Bi-lobed nucleus, Dark pink stained granules
Describe Basophils
Bi-lobed nucleus that usually can’t be seen, Lots of dark purple stained cytoplasmic granules that take up the entire cell
Describe Monocytes
Kidney-shaped nucleus, no granules, cytoplasm is very faintly stained blue
Describe Lymphocytes
Large, spherical nucleus, no granules, thin outer rim of faintly blue-stained cytoplasm
What phrase do we use for the order of WBC’s in terms of normal numbers found in blood? Name the WBC’s associated with each letter of the phrase.
Never Let Monkeys Eat Bananas
N(eutrophils)
L(ymphocytes)
M(onocytes)
E(osinphils)
B(Basophils)
Hemostasis
A process to prevent and stop bleeding, keeping blood in a damaged blood vessel. It’s the first stage of wound healing.
The phases of hemostasis
- Vascular Phase
- Platelet Phase
- Coagulation Phase
What happens during the Vascular Phase?
Vascular spasm of smooth muscle of vessel walls, membranes become sticky
What happens during the Platelet Phase?
Platelets stick to sticky membrane, collagen fibers, and each other
What happens during the Coagulation Phase?
Complex sequence of steps changing fibrinogen to fibrin and forming a clot
What catalyzes (speeds up) the reaction converting fibrin to fibrinogen?
Thrombin
What happens to a clot during fribrinolysis
It dissolves
Fibrinolysis
A process that prevents blood clots that occur naturally from growing and causing problems.
Describe Sickle Cell Anemia.
It’s a recessive (need two 2 defective copies of gene) genetic disorder where RBC’s are sickle shaped which makes them fragile and easily damaged. Sickled RBC’s can clog narrow vessels. Gene to look out for is low hemoglobin levels.