Blood Flashcards
What are the two main components of blood?
✔️Plasma
(non-living fluid matrix)
✔️Formed Elements
(living blood “cells” suspended in plasma)
What type of tissue is ‘Blood’?
Connective Tissue
The only “true cells” that are considered blood cells are _______.
Leukocytes
A spun tube of blood yields what percentages of what three layers?
55% Plasma (least dense)
1% Buffy Coat
45% Formed Elements (Erythrocytes)
What is the composition of plasma?
1⃣ 90% Water
2⃣ Solutes
✔️ 8% Plasma Proteins
• 60% Albumin
• 36% Globulins
*alpha, beta, gamma
•4% Fibrinogen
✔️Non-Protein Nitrogenous Substances
- Nutrients
- Electrolytes
- Respiratory Gases
- Hormones
Name the
Three (3)
Main Functions of Blood
- Distribution
- Regulation
- Protection
Name the
Three (3)
Distribution Functions of Blood
- Delivery to All Body Cells:
✔️Oxygen from Lungs
✔️Nutrients from Digestive Tract - Transport Metabolic Waste From Cells to Elimination Sites:
✔️Carbon Dioxide to Lungs
✔️Nitrogenous Wastes to Kidneys (Urine) - Transporting Hormones
✔️From Endocrine Glands to Target Organs
Name the Three (3) Regulatory Functions of Blood
- Maintain appropriate body temperature
- Maintain normal pH in tissues
(7. 35 - 7.45) - Maintain adequate fluid volume in the Circulatory System
Blood acts as a reservoir for the body’s __________________ of bicarbonate atoms.
Alkaline Reserve
___________ and ___________ act to prevent excessive fluid loss from the bloodstream into the tissue spaces.
Salts and Blood Proteins
Name the Two (2) Protective Functions of Blood
- Preventing Blood Loss
2. Preventing Infection
How does blood protect the body from blood loss?
When a blood vessel is damaged, platelets and plasma proteins initiate clot formation, halting blood loss.
How does the blood function in protecting the body against infection?
Blood carries antibodies, complement proteins, and white blood cells, which help defend the body against bacteria and viruses.
What is the most common plasma protein and what is it’s percentage of the plasma proteins?
Albumin; makes up 60% of plasma proteins
Where is Albumin produced and what is it’s function?
✔️Produced By the Liver
✔️Important Blood Buffer
✔️Main Contributor to Osmotic Pressure (helps to keep water in bloodstream)
✔️Carries Certain Molecules Through Circulation
Which two (2) body systems are primarily called into action when the blood becomes too acidic (acidosis)?
- Respiratory System
2. Kidneys
What is the Hematocrit?
Percentage of blood volume that is RBC’s
Name the Three (3) Formed Elements of Blood
- Erythrocytes (RBC’s)
- Leukocytes (WBC’s)
- Platelets
Erythrocyte
RBC
✔️Functions in gas transport
✔️”Bags” of Hemoglobin (Hb)
✔️Lack nucleus (anucleate)
✔️Biconcave shape
Hematocrit Value for Males
47% +/- 5%
Hematocrit Value for Females
42% +/- 5%
Blood Volume makes up ____% of body weight.
8%
Normal Range of Blood pH
pH 7.35 - 7.45
Blood color varies based on _____________.
Oxygen Content
(High O2 = Bright/Scarlet Red)
(Low O2 = Dark Red)
Average Blood Volume for Males
5 - 6 Liters
Average Blood Volume for Females
4 - 5 Liters
What structural characteristics of the Erythrocyte contribute to gas transport?
✔️Biconcave shape
✔️97% Hemoglobin
✔️Anaerobic ATP production/No Mitochondria
(Do not consume the O2 they transport)
Define Spectrin
A plasma membrane protein that provides the Erythrocytes with the flexibility to change shape as they pass through tiny capillaries.
The blood cell that can become an antibody-secreting cell is the ________________.
Lymphocyte
Normal RBC Value for Males
13 - 18g / 100 ml
Normal RBC Value for Females
12 - 16g / 100 ml
Which plasma protein is involved in immunity?
Gamma Globulins
Name the Eight (8) Functions of Blood
- Deliver O2 and nutrients to cells
- Transport metabolic waste to lungs and kidneys
- Transport hormones from endocrine organs to target organs
- Maintain body temperature by absorbing and distributing heat
- Maintain normal pH by using buffers (alkaline reserve of bicarbonate ions)
- Maintain fluid volume in circulatory system
- Prevent blood loss by the initiation of clot formation via plasma proteins and platelets
- Prevent infection via antibodies, WBC’s, and complement proteins
Which body organ is responsible for the production of plasma proteins?
Liver
What is the significance of he RBC’s biconcave shape?
It is the most efficient design to release oxygen due to its large surface area relative to volume.
How many iron atoms are carried by a hemoglobin molecule?
Four (4) Iron Atoms
Hemoglobin Structure:
“Heme”
✔️ is the “iron part”
✔️Pigment bonded to each “Globin” Chain which gives blood it’s red color
✔️Central iron atom binds one O2
Hemoglobin Structure:
“Globin”
✔️ is the “Protein Part”
✔️ Carries some CO2
✔️ Composed of 4 polypeptide chains
• 2 Alpha and 2 Beta