Blood Flashcards
Red Blood Cells are also known as?
Erythrocytes
What compounds are dissolved/suspended in blood? (5)
O2 Electrolytes Hormones Drugs Nutrients
White Blood Cells are also known as?
Leukocytes
Platelets are also known as?
Thrombocytes
What is the term whole blood used for
Blood contained in the cardiovascular system or a sample that contains all blood parts
What is peripheral blood?
Whole blood that flows through the blood vessels (heart & lungs)
What makes up the fluid portion of a blood sample?
Plasma
Plasma makes up between how much %?
45-78%
What % of plasma is water?
93%
Name 3 plasma proteins
- Albumin
- Globulins
- Fibrinogen
Why is blood red?
Hemoglobin
Hemoglobin gives blood what ability?
Enables red blood cells to carry lathe amounts of oxygen
Name a break down product of hemoglobin
Bilirubin
Name 3 cellular components of blood
- Red blood cells
- White blood cells
- Platelets
Name the 5 types of WBCs
- Eosinophils
- Basophils
- Neutrophils
- Monocytes
- Lymphocytes
Name the 2 white blood cells that don’t have granules
Monocytes and lymphocytes
Basic cell structures will stain what color
Blue
Acidic cell structures will stain what color
Red
Hematopoiesis means
Production of all blood cells
In an early fetus, hematopoiesis takes place where (2)
Liver & slpeen
As the fetus develops this gradually takes over production of the blood cells
Bone marrow
This organ will swell up and store blood until its needed
Spleen
Do RBCs have a nucleus?
No
What color do RBCs stain?
Red due to hemoglobin
This species of animal has the largest RBCs
Dogs
Llamas and camels have this shape RBCs
Oval
Is hemoglobin a protein?
Yes
Hemoglobin is a protein composed of these two components
Heme and globin
Heme is produced in?
The mitochondria
Globin is produced by
Ribosomes
This hemoglobin protein is the pigment portion
Heme
This hemoglobin protein is the protein portion
Globin
What is the major function of hemoglobin?
Transport oxygen to tissues
Name 4 factors that influence hemoglobins ability to carry oxygen
- pH
- Temperature
- Oxygen
- Carbon dioxide levels
The life span of RBCs in dogs last how many days
110
The life span of RBCs in cats last how many days
68
The life span of RBCs in horse/sheep last how many days
150
The life span of RBCs in cows last how many days
160
The life span of RBCs in mice last how many days
20-30
The life span of RBCs in humans last how many days
120
RBCs are replaced by young RBCs produced from where?
Bone marrow
The process of aging is called
Senescence
The distraction of RBCs is done by
Macrophages
What is anemia
Decreased O2 carrying capacity of the blood
Anemia can be caused by 2 factors, they are?
- Low number of circulating mature RBCs
2. Not enough hemoglobin being produced
Polycythemia means
Above normal RBCs
Name the 3 types of polycythemia
- Relative polycythemia
- Compensitory polycythemia
- Polycythemia rubra vera
Compensitory polycythemia is a result of?
Hypoxia
Relative polycythemia is seen when?
There is a loss of fluid from blood
Polycythemia Rubra Vera is a rare bone marrow disorder characterized by?
Increased production of RBCs
Production of platelets is called
Thrombopoiesis
Platelets contains this which is necessary for blood to clot
Clotting factors and calcium
Name the 3 rolls platelets have in the clotting process
- Maintenance of vascular integrity
- Platelet plug formation
- Stabilization of the hemostatic plug by contributing to fibrin formation
White blood cells can be classified in 3 ways, they are?
- Type of defense function
- Shape of nucleus
- Granulocytes or agranulocytes
Term used for the formation of WBCs is
Leukopoiesis
WBC formation starts out where?
In the red bone marrow
The functions of WBCs is to?
Provide a defense for the body against foreign invaders
Acidic cells stain pink, which WBC will stain pink?
Eosinophils
Basic cells stain blue, which WBC stains blue?
Basophil
This WBC appears colorless when stained
Neutrophils
What is the name of the most numerous WBC found in dogs, cats, horses?
Neutrophils
Where are neutrophils produced?
In the bone marrow
(True/False) Neutrophils are phagoytes meaning they engulf microorganisms and other debris in tissue
True
Eosinophils are produced where?
In the bone marrow
Name 3 main functions of eosinophils
- Anti inflammatory
- Immunity
- Phagocytosis
(True/False) Basophils are the least often seen WBC
True
Name the two things responsible for basophil function
- Histamine
2. Heparin
Histamine helps:
Initiate inflammation and acute allergic reactions
Heparin acts as a?
Localized anticoagulant
This WBC is the largest in circulation
Monocytes
When monocytes enter the tissue they become known as?
Macrophages
Name 3 functions of monocytes
- Clean cellular debris
- They process certain antigens
- They ingest foreign substances
Lymphocytes are normally the predominant WBC in circulation in
Ruminants (sheep, cattle, goats) and pigs
This WBC has no phagocytic capabilities
Lymphocytes
Name the 3 different types of lymphocytes
- T cells
- B cells
- Natural killer cells
Both these types of lymphocytes can become memory cells
T & B cells
T & B cells don’t participate in an initial immune response however they do this
Wait in tissue waiting for a second exposure to the same antigen
When the tissue is exposed to an antigen a second time, these cells respond quicker than the initial response
T & B cells
Increased number of lymphocytes in peripheral blood is known as
Lymphocytosis
Lymphocytosis can result from
Leukemia
Chronic infection
Epinephrine release
Decreased number of lymphocytes in blood is called
Lymphopenia
This system is a series of vessels or ducts that carries excess tissue fluid to blood vessels near the heart
Lymphatic
These capillaries gather up the excess fluid and carry it away
Lymph
A lymph node is divided into what two parts?
Cortex and medulla
This is where the lymphocytes reside
The cortex
Clustered groups of lymphocytes are called
Lymph nodules