Blood Flashcards
Blood Function
Distribution, Regulation, Protection
Blood Composition
Plasma 55%- non-living fluid matrix
Erythrocytes 45%- living blood cells
Leukocytes- white blood cells
Platelets- cell fragments
Plasma
> 90% water
100 dissolved solutes
Albumin
Helps with osmotic balance and buffers PH
Globulin
Helps in immune response and lipid transport
Fibrinogen
Helps with Blood Clotting
Leukocytes
Complete cells
Make up <1% of total blood volume
Leukocytosis
WBC count > 11,000/ mu liter
Diapedesis
Passing of blood through intact capillaries
Order of Abundance
Never Let Monkeys Eat Bananas
Neutrophils, Lymphocytes, Monocytes, Eosinophils, Basophils
Neutrophils
Aka Polymorphonuclear leukocytes
Very phagocytic
Eosinophils
Lysosome-like granules
Deals with allergies, asthma, and general immune response
Basophils
Changes size of blood vessels
Granules contains histamine
Histamine
Inflammatory chemical -> vasodilator
Lymphocytes
Mostly in Lymphoid tissue
Help in immune response
T-Lymphocytes
Fights against virus-infected and cancer cells
B-Lymphocytes
Anti-body producing cells
Monocytes
Macrophages
Active phagocytic cells
Platelets
Cytoplasmic fragments of megakaryocytes
Act in clotting process
Formation regulated by thrombopoietin
Erythrocytes
Simple biconcave discs
Filled with hemoglobin for gas transport
Contains plasma membrane protein spectrin
Gas Transport in RBC
Hemoglobin binds reversibly with oxygen (it can pick up and drop it off)
Hemoglobin Structure
Consists of globin (two alpha and two beta polypeptide chains and four gene groups)
Oxyhemoglobin
Oxygenated blood
Ruby red color
Deoxyhemoglobin
Unoxygenated blood
Dark red color
Carbaminohemoglobin
Carbon bonds to amino acid chain
20% of CO2 in blood binds to hemoglobin
Erythrocyte structure and function
Biconcave shape
>97% hemoglobin
No mitochondria, ATP produced anaerobicly
Hematopoiesis
Blood Cell Formation
In adults, axial skeleton, girdles and proximal epiphyses of humerus and femur
Hemocytoblasts
Hematopoietic stem cells
Gives rise to all formed elementa