Block 3 Flashcards
Acronym: DEJ
dermal-epithelial junction
- attaches dermis to epidermis
- provides increased surface area and connection points for nutrient exchange and signaling
Acronym: McSCc
melanocyte stem cells
- cells that give rise to melanocytes
Acronym: HPA Axis
hypothalamic-pituitary-adrenal axis
- feedback loop that manages the body’s stress response system
Acronym: CRH
corticotropin releasing hormone
- part of the HPA axis that responds to increase stress through a positive feedback loop that signals the anterior pituitary gland
Acronym: ACTH
adrenocorticotropic hormone
- part of the HPA axis that responds to the signal from hypothalamus and CRH, bringing it to the adrenal glands
Acronym: FMP
final menstrual period
- marks the beginning of menopause and occurs around age 51.4
Acronym: FSH
follicle stimulating hormone
- acts on granulosa (women) and sertoli (men) cells to stimulate follicle growth and hormone production
Acronym: LH
luteinizing hormone
- acts on theca (women) and leydig (men) cells to stimulate hormone production
Acronym: HPG Axis
hypothalamus-pituitary-gonadal axis
- feedback loops between hypothalamus, pituitary gland, and ovaries (women) and testis (men)
Acronym: GnRH
gonadotropin hormone releasing hormone
- part of the HPG axis and is secreted from the hypothalamus to the anterior pituitary gland
Acronym: BMI
body mass index
- measures body fat based on height and weight and can be used as an indicator for when an individual may have the first or last period
Acronym: HRT
hormone replacement therapy
- restoring hormone levels lost as a result of aging
Acronym: WHI
women’s health initiative
- ~1975 pure estrogen in high concentrations was used for estrogen lost from menopause
Acronym: SHBG
sex hormone binding globulin
- defines free vs total testosterone in men and is considered free when testosterone is NOT bound to SHBG
Acronym: TRT
testosterone replacement therapy
- used in men to replace testosterone lost over time
Acronym: ERT
estrogen replacement therapy
- used in women to replace estrogen lost as a result of menopause