Block 2 April Flashcards
Diagnostic criteria for intellectual disability:
IQ at or below 70
brief episode of intense fear accompanied by physical symptoms:
panic attack
anxiety or distress over leaving home:
Agoraphobia
increased activity where in OCD?
frontal cortex
aggression to people and animals
destruction of property
deceitfulness or theft
serious violations of rules
childhood or adolescent onset
conduct disorder
loses temper
argues with adults
deliberately annoys people
blames others
touchy or easily annoyed
anger and resent
spiteful or vindictive
oppositional defiant disorder
Treatment of anxious alcoholics:
buspirone
Mania lasting 7 days
Bipolar 1
Hypomania lasting 4 days
Bipolar 2
Tx for adolescent depression
SSRIs for at least 1 year
**Tricyclics are contraindicated
Cluster A personality disorders:
weird
Cluster B personality disorders:
wild
Cluster C personality disorders:
worried
pervasive distrust and suspiciousness of others
Paranoid
cluster A
detatchment or disinterest in social relationships
schizoid
cluster A
acute discomfort with and reduced capacity for close relationships
magical thinking
schizotypal
cluster A
instability of interpersonal relationships
impulsivity
intense episodic dysphoria
borderline PD
cluster B
grandiosity
need for admiration
lack of empathy
narcissistic
cluster B
disregard and violation of the rights of others
antisocial PD
cluster B
**kind of like conduct disorder after adolescence
excessive emotionality and attention seeking
Histrionic PD
cluster B
pervasive pattern of social inhibition
Avoidant PD
cluster C
pervasive need to be taken care of
dependent PD
cluster C
preoccupation with orderliness
Obsessive compulsive PD
cluster C
only agents to have anti-suicide effects in bipolar disorder
clozapine
lithium (first line)
mood stabilizers
Lithium
Divalproex
Carbamazepine
Pathophysiology of schizophrenia:
increased dopamine
First atypical (2nd gen) antipsychotic:
clozapine
benefit of 2nd gen antipsychotics
treat positive AND negative sx
lots of outpatient visits
frequent hospitalizations
repetitive subspecialty referrals
lots of diagnoses
multiple meds
Somatic Symptom disorder
Physical symptoms following stress event
ie. paralysis after witnessing death
Conversion disorder
intentionally exaggerates or induces signs and symptoms of illness
motivation is to assume the sick role
no other incentive for illness
Factitious disorder
severe factitious disorder
Munchausen syndrome
use of approximate answers in factitious disorder
Ganser’s syndrome
lying about illness motivated by external incentives
Malingering
most common side effect of SSRIs:
sexual dysfunction
5HT2/3 blocker with less sexual side effects and less anxiety:
Mirtazepine
antidepressant
no weight gain
less sexual side fx
not good for anxiety unless smoker
busproprion
Genetic polymorphism linked to Major Depressive Disorder
5HTTLPR
Long + Long promoter on 5HTTLPR gene = ?
low depression
1st line for MDD?
SSRIs
Dopamine-norepinephrine reuptake inhibitor?
What is it NOT used for?
Bupropion
Anxiety (CONTRAindicated)
Also blocks post synaptic serotonin receptor:
mirtazapine
More effective than SSRIs/SNRIs but lethal in OD:
tricyclics
monoamine oxidase inhibitor
phenelzine
blocks NMDA receptors
ketamine