Block 2 Flashcards
What initiates the development of the lymph nodes?
The LEC(Lymphatic Endothelial Cells) leak out of the blood vessels.
Nodules are formed when the LEC’s aggregate and form ________ with mesenchyme.
Lymph sacs
Nodes are formed when the nodules become surrounded by _____.
sinuses
What are the two types of lymphocytes that reside in the node?
B and T
Lymphatic cells migrate to node from which 3 areas?
mesenchyme, thymus, and Marrow
The lymph node is surrounded by a capsule and bands of connective tissue called ________ that extend into the capsule and node.
trabeculae
Lymph fluid is received from _____ lymphatic vessels
then flows over nodules of lymphocytes.
afferent
Filtered lymph collects in the medulla then drains out an _________lymphatic vessel at the _____ of the node.
efferent
hilum
How is extracellular fluid collected into the lymph system?
Hydrostatic pressure in capillaries
Does lymph collected in the capillaries return to the arterial or venous system?
Venous
Tonsils are formed from lymph ____.
sacs
What type of lymphatic tissue do tonsils contain?
unencapsulated
What type of epithelium are tonsils covered in?
nonkeratinized stratified squamous epithelium
What is the purpose of a tonsillar crypt?
To increase surface area
What is the clinical diagnosis of debris collection or calcification within a tonsillar crypt?
Tonsilloliths
What is the purpose of the tonsillar ring?
Immunologic “First pass” protection at the common entrance of the digestive and respiratory tracts
What are the 4 main tonsils of the tonsillar ring?
Adenoids (pharyngeal), tubal, palentine, lingual
What are the three major salivary glands?
Parotid, submandibular, sublingual
How does the Parotid gland develop?
From an invagination of ectoderm between the maxillary and mandibular swellings
True or False
Saliva glands are formed from epithelial-mesenchymal interactions
True
What are the two types of salivary gland secretions?
Serous and Mucous
Serous saliva is thin/watery and contains which 3 major components?
Enzymes, lactoferrin and immunoglobulin A (to neutralize bacteria)
Thicker, mucous type saliva is generally produced in response to what kind of stimuli, parasympathetic or sympathetic?
Sympathetic
Is saliva hypotonic or hypertonic?
Hypotonic
True or False Saliva contains the following: Electrolytes Amylase Lipase Lactoferrin Immunoglobulin A Lysozyme Mucous SLIPI
True
Name the 3 types of salivary ducts
Intercalated, Striated, and Excretory
Describe the type of epithelium found in each type of salivary duct
Intercalated : simple cuboidal epithelium
Striated: simple cuboidal to columnar epithelium
Excretory: simple cuboidal to columnar epithelium and occasionally stratified columnar epithelium
The Intercalated salivary duct is responsible for receiving fluid from the _______.
acinus
The striated salivary duct creates a more hypotonic solution by removing _____ and secreting _____ into the saliva.
NaCl (salt)
Bicarbonate (HCO3-)
What is the function of the excretory duct?
To transport/connect the saliva with the oral cavity
Where could you find minor salivary glands?
Present throughout the tongue and lining the oral mucosa
Minor salivary glands produce antimicrobial agents such as ____.
Lysozyme
If minor salivary glands become damaged they form ____.
Mucoceles
Where are the Parotid glands located on the face?
Lateral boarder of face and anterior to the ear
Which are the largest salivary glands?
Parotid
Are the parotid glands primarily mucous or serous secreting?
Serous (stains dark on slides)
What percentage of saliva is produced by each gland?
Salivary 25%
Submandibular 70%
Sublingual 5%
Which disease can affect the parotid glands?
Mumps
Where are the submandibular glands located on the face?
Lateral boarder of the mandible
Are the submandibular glands mucous or serous secreting?
It is a mixed gland and therefore has both types of cells
Where are the sublingual glands located?
Below the anterior portion of the tongue
Are the sublingual glands predominately mucous or serous secreting?
Mucous (although it does have both type of cells)
The salivary glands can become clogged with calcification. This condition is known as _____.
Salivary Gland Stones or Sailolithiosis
What is the treatment for sailolithiosis?
Prevention is with hydration
Gland massage
Sour lemon juice to increase salivary flow