Block 1 - Immunology Flashcards
What are the 5 basic targets of the immune system?
Viruses, bacteria, fungi, protozoa, parasites
Intracellular invaders are ____ and ____ generally
Viruses, cancer
What are the four features of the INNATE immune system that work on fighting microbes?
Inflammatory mediators, phagocytic cells, interferons, complement
What are the two features of the ADAPTIVE immune system that work on the fighting microbes?
T-cells, B-cells (cytokines)
The cells involved in our immune response are the____, ____, and ____.
phagocytic cells, T-cells, and B-cells
The proteins involved in our immune response are the____, ____, and ____.
Interferons, complement, immunoglobulins (from B-cells)
The chemical mediators involved in our immune response are the ____ and ____
Inflammatory mediators, cytokines
Leukocyte site of action are ____ their targets are ____ and they respond ____
Local, non-specific, fast/first
Lymphocyte site of action are ____ their targets are ____ and they respond ____
Global, specific epitope, slow/last
After an adaptive response, ____ cells are are produced
Memory
What bones generally start to lose RBC production capabilities by age 30?
Long bones
Leukocytes get to the site of invasion using what mechanism of “rolling”?
Margination
A neutrophil squeezing between endothelial cells is called…?
Diapedesis
When comparing neutrophils (N) to macrophages (M)…there are ____ neutrophils than macrophages. Neutrophils are found in ____ tissue while macrophages are found in ____ tissue as well as ____ tissue. Neutrophils live ____ than macrophages. Neutrophils kill ____ invading cells than macrophages.
More, unhealthy, healthy, unhealthy, shorter, less
Interferons are generally induced by the presence of a ____
Virus
