Blisters Flashcards

1
Q

Reversed

Fragility of Epithelium

Bulla formation

Severity ranges between ‘simple’ ‘dystrophic’ and ‘lethalis’ forms of the disease

A

Epidermolysis Bullosa

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2
Q

Pemphigus

A

Areas of erosion at any mucosal site

Non-keratinized sites more frequently affected

Vesicles are present however, rarely seen due to early rupture

Usually found in older people, more common in females rather than males.

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2
Q

Reversed

Rapidly bursting Blisters

Blood crusted lips

Widespread painful ulceration

Swollen and erythmatous gingivae

Pyrexia, Cervical Lymphadenopathy and Headache

Differential Diagnosis

Herpetiform RAS

Recurrent HSV Infection

A

Primary Herpetic Gingivostomatitis

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3
Q

Herpangina

A

Vesicular eruptions on Soft Palate

Fauces

Tonsils

Diffuse Erythematous Pharyngitis

Malaise, Fever and Sore Throat

Resolution can be expected in 7-10 days

Differential Diagnosis

Hand, Foot and Mouth disease

VZV

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3
Q

Reversed

Macular and Vesicular eruptions on Hands, Feet and Mucosa of:

Pharynx

Soft Palate

Buccal Sulcus

Tongue

Usually asymptomatic and resolves in 7-10 days.

Differential DIagnosis:

Primary Herpetic Gingivostomatitis

VZV Infection.

A

Hand, Foot and Mouth Disease

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4
Q

Reversed

Areas of erosion at any mucosal site

Non-keratinized sites more frequently affected

Vesicles are present however, rarely seen due to early rupture

Usually found in older people, more common in females rather than males.

A

Pemphigus

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6
Q

Primary Herpetic Gingivostomatitis

A

Rapidly bursting Blisters

Blood crusted lips

Widespread painful ulceration

Swollen and erythmatous gingivae

Pyrexia, Cervical Lymphadenopathy and Headache

Differential Diagnosis

Herpetiform RAS

Recurrent HSV Infection

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7
Q

Reversed

Crops of Blisters on skin & oral mucosa

Can be preceded by erythematous patches

Lesions are exceedingly pruritic (Itchy)

Differential Diagnosis

Linear IgA

Pemphigus

A

Dermatitis Herpetiformis

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8
Q

Reversed

Vesicular eruptions on Soft Palate

Fauces

Tonsils

Diffuse Erythematous Pharyngitis

Malaise, Fever and Sore Throat

Resolution can be expected in 7-10 days

Differential Diagnosis

Hand, Foot and Mouth disease

VZV

A

Herpangina

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8
Q

Reversed

Painless, fluid filled swelling

Blue discoloration

Smooth surface

Usually found on the lip

A

Mucocele

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10
Q

Chickenpox and Shingles

A

Maculopapular skin rash

Start on trunk and spread to face and limbs

Skin lesions may be preceded by oral ulcers of <5mm

**Reactivation of VZV **

Sever pain

Vesicobullous lesions

One branch of Trigeminal nerve may be affected in 15% of cases.

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10
Q

Reversed

Persistant, non-specific

Ulceration

Skin lesions occur elbows, buttocks and scalp

Differential DIagnosis:

Mucous Membrane Pemphigoid

Dermatitis Herpetiformis

A

Linear IgA disease

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11
Q

Dermatitis Herpetiformis

A

Crops of Blisters on skin & oral mucosa

Can be preceded by erythematous patches

Lesions are exceedingly pruritic (Itchy)

Differential Diagnosis

Linear IgA

Pemphigus

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12
Q

Reversed

Sub-epithelial bulla formation

Areas of painful mucosal ulceration

desquamitive gingivitis

‘lining of the mouth peeling off’

A

Mucous Membrane Pemphigoid

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14
Q

Mucous Membrane Pemphigoid

A

Sub-epithelial bulla formation

Areas of painful mucosal ulceration

desquamitive gingivitis

‘lining of the mouth peeling off’

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15
Q

Reversed

Blood-crusted lips

Widespread painful oral ulceration

‘Target-lesions’ on Skin

Lymphadenopathy

Usally spontaneously resolve in 10-14 days

Pts may find 2-3 episodes of recurrence within 2-3 years of original episode.

Differential DIagnosis:

Primary Herpetic Gingivosomatitis

A

Erythema Multiforme

16
Q

Erythema Multiforme

A

Blood-crusted lips

Widespread painful oral ulceration

‘Target-lesions’ on Skin

Lymphadenopathy

Usally spontaneously resolve in 10-14 days

Pts may find 2-3 episodes of recurrence within 2-3 years of original episode.

Differential DIagnosis:

Primary Herpetic Gingivosomatitis

17
Q

Linear IgA disease

A

Persistant, non-sprecific

Ulceration

Skin lesions occur elbows, buttocks and scalp

DIfferential DIagnosis:

Mucous Membrane Pemphigoid

Dermatitis Herpetiformis

18
Q

Reversed

Maculopapular skin rash

Start on trunk and spread to face and limbs

Skin lesions may be preceded by oral ulcers of

**Reactivation of VZV **

Sever pain

Vesiocobullous lesions

One branch of Trigeminal nerve may be affected in 15% of cases.

A

Chickepox and Shingles

19
Q

Reversed

Tingling or burning sensation on lips

Crop of vesicles present on lips

Within 48 hours - vesicles rupture to leave erosion that crusts over

Heals within 7-10 days

HSV virus can also be reactivated on Hard Palate, gingival margins and buccal sulcus.

Differential Diagnosis:

Primary herpetic gingivostomatitis

A

Recurrent Herpes Simplex Infection

20
Q

Mucocele

A

Painless, fluid filled swelling

Blue discoloration

Smooth surface

Usually found on the lip

22
Q

Angina Bullosa Hemorrhagica

A

Solitary blood-filled blister

Rapidly appears

Pts complain of ‘tightness’ in area

Invariably develops during eating

Differential Diagnosis:

Epidemolysis Bullosa

23
Q

Recurrent Herpes Simplex Infection

A

Tingling or burning sensation on lips

Crop of vesicles present on lips

Within 48 hours - vesicles rupture to leave erosion that crusts over

Heals within 7-10 days

HSV virus can also be reactivated on Hard Palate, gingival margins and buccal sulcus.

Differential Diagnosis:

Primary herpetic gingivostomatitis

24
Q

Reversed

Solitary blood-filled blister

Rapidly appears

Pts complain of ‘tightness’ in area

Invariably develops during eating

Differential Diagnosis:

Epidemolysis Bullosa

A

Angina Bullosa Hemorrhagica

25
Q

Hand, Foot and Mouth Disease

A

Macular and Vesicular eruptions on Hands, Feet and Mucosa of:

Pharynx

Soft Palate

Buccal Sulcus

Tongue

Usually asymptomatic and resolves in 7-10 days.

Differential DIagnosis:

Primary Herpetic Gingivostomatitis

VZV Infection.

26
Q

Epidermolysis Bullosa

A

Fragility of Epithelium

Bulla formation

Severity ranges between ‘simple’ ‘dystrophic’ and ‘lethalis’ forms of the disease