Blisters Flashcards
Reversed
Fragility of Epithelium
Bulla formation
Severity ranges between ‘simple’ ‘dystrophic’ and ‘lethalis’ forms of the disease
Epidermolysis Bullosa
Pemphigus
Areas of erosion at any mucosal site
Non-keratinized sites more frequently affected
Vesicles are present however, rarely seen due to early rupture
Usually found in older people, more common in females rather than males.
Reversed
Rapidly bursting Blisters
Blood crusted lips
Widespread painful ulceration
Swollen and erythmatous gingivae
Pyrexia, Cervical Lymphadenopathy and Headache
Differential Diagnosis
Herpetiform RAS
Recurrent HSV Infection
Primary Herpetic Gingivostomatitis
Herpangina
Vesicular eruptions on Soft Palate
Fauces
Tonsils
Diffuse Erythematous Pharyngitis
Malaise, Fever and Sore Throat
Resolution can be expected in 7-10 days
Differential Diagnosis
Hand, Foot and Mouth disease
VZV
Reversed
Macular and Vesicular eruptions on Hands, Feet and Mucosa of:
Pharynx
Soft Palate
Buccal Sulcus
Tongue
Usually asymptomatic and resolves in 7-10 days.
Differential DIagnosis:
Primary Herpetic Gingivostomatitis
VZV Infection.
Hand, Foot and Mouth Disease
Reversed
Areas of erosion at any mucosal site
Non-keratinized sites more frequently affected
Vesicles are present however, rarely seen due to early rupture
Usually found in older people, more common in females rather than males.
Pemphigus
Primary Herpetic Gingivostomatitis
Rapidly bursting Blisters
Blood crusted lips
Widespread painful ulceration
Swollen and erythmatous gingivae
Pyrexia, Cervical Lymphadenopathy and Headache
Differential Diagnosis
Herpetiform RAS
Recurrent HSV Infection
Reversed
Crops of Blisters on skin & oral mucosa
Can be preceded by erythematous patches
Lesions are exceedingly pruritic (Itchy)
Differential Diagnosis
Linear IgA
Pemphigus
Dermatitis Herpetiformis
Reversed
Vesicular eruptions on Soft Palate
Fauces
Tonsils
Diffuse Erythematous Pharyngitis
Malaise, Fever and Sore Throat
Resolution can be expected in 7-10 days
Differential Diagnosis
Hand, Foot and Mouth disease
VZV
Herpangina
Reversed
Painless, fluid filled swelling
Blue discoloration
Smooth surface
Usually found on the lip
Mucocele
Chickenpox and Shingles
Maculopapular skin rash
Start on trunk and spread to face and limbs
Skin lesions may be preceded by oral ulcers of <5mm
**Reactivation of VZV **
Sever pain
Vesicobullous lesions
One branch of Trigeminal nerve may be affected in 15% of cases.
Reversed
Persistant, non-specific
Ulceration
Skin lesions occur elbows, buttocks and scalp
Differential DIagnosis:
Mucous Membrane Pemphigoid
Dermatitis Herpetiformis
Linear IgA disease
Dermatitis Herpetiformis
Crops of Blisters on skin & oral mucosa
Can be preceded by erythematous patches
Lesions are exceedingly pruritic (Itchy)
Differential Diagnosis
Linear IgA
Pemphigus
Reversed
Sub-epithelial bulla formation
Areas of painful mucosal ulceration
desquamitive gingivitis
‘lining of the mouth peeling off’
Mucous Membrane Pemphigoid
Mucous Membrane Pemphigoid
Sub-epithelial bulla formation
Areas of painful mucosal ulceration
desquamitive gingivitis
‘lining of the mouth peeling off’