BLI 2 - Erythropoiesis & Diagnosis (Siddiqui) Flashcards
RBC shape: Multiple, blunt, rounded projections [liver disease, abetalipoproteinemia]
Acanthocyte
RBC shape: Target cell [asplenia, HbC disease, liver disease]
Codocyte
RBC shape: Tear drop cell [myelofibrosis]
Dacrocyte
RBC shape: Bite cell [G6PD deficiency]
Degmacyte
RBC shape: Sickle cell [sickle cell anemia]
Drepanocyte
RBC shape: Short, evenly-spaced, sharp surface projections [kidney disease, EDTA artifact, pyruvate kinase deficiency]
Echinocyte
RBC shape: oval-shaped [iron deficiency]
Elliptocyte
RBC shape: Fragmented RBC, helmet cell [DIC, TTP/HUS]
Schistocyte
RBC shape: Dense cell lacking central pallor [autoimmune hemolytic anemia, hereditary spherocytosis]
Spherocyte
RBC shape: Fish mouth-shaped [hereditary stomatocytosis, artifact]
Stomatocyte
RBC inclusion: ribosomes & polyribosomes
Basophilic stippling
RBC inclusion: residual microtubules from mitotic spindle
Cabot rings
RBC inclusion: denatured, precipitated hemoglobin, requires supravital stain
Heinz bodies
RBC inclusion: result of oxidant hemolysis
Heinz bodies
RBC inclusion: rod-shaped, dense-staining
Hemoglobin C crystals