Bleeding in Pregnancy Flashcards
Anemia Definition
low number of RBCs or a low number in the concentration of circulating blood
Diagnosis of Anemia in Pregnancy
- 1st trimester Hgb <11 g/dl
- 2nd trimester Hgb <10.5 g/dl
- 3rd trimester Hgb <11 g/dl
By law, when do we have to consult, refer, or transfer for anemia?
H/H
- Less than 31% or 10.3 gm/100 ml
- Less than 28% or 9.3 gm/100 ml.
- Sickle cell anemia.
How can Anemia physiologically occur during pregnancy?
Hemodilution
What is Hemodilution?
The increase in blood volume increases the plasma in the blood more than RBCs
What are the etiologies of anemia?
- iron deficiency
- vitamin B12 deficiency
- folate acid deficiency
S/S of nutritional anemia
- asymptomatic
- fatigue
- drowsy
- malaise
- dizziness
- weakness
- sore tongue
- pallor, pale mucous membranes
- SOB
- appetite loss
- cold hands and feet
- trouble concentrating
What is the most common anemia?
Iron Deficiency
What does iron rich anemia increase the risk of?
- low birth weight
- preterm delivery
- perinatal mortality
- postpartum depression
Anemia diagnosis labs
- low serum ferritin and serum iron
- High TIBC or [RDW]
What is hematocrit?
it is the percentage of RBC in your blood or percentage of RBC volume compared to your total blood volume
Summary of normal hematological changes in pg
- plasma volume increase by 50 percent
- Red cell mass [total volume of red cells in circulation] increases by 20 percent
- physiological anemia of pg- as a result of the dilution effect of greater plasma increase in relation to increase in RBC
- WBC increase
- hypercoagulable state- changes to coagulation and fibrinolysis
- venous stasis
- isolated mild thrombocytopenia- platelet count tends to fall progressively to lower threshold of normal or below, near term, needs to be distinguished from pathological causes such as pre-e
- significant increase in requirement for iron, folate, and vit B12
what is RBC job
they contain significant amounts of hemoglobin and their primary function is to transport oxygen in the blood.
what does RBC maturation depend on
formed in the bone marrow, and their maturation is dependent on the presence of iron, vitamin B12, and folic acid, which are derived from the diet.
how long does a RBC last
they survive on average for just 120 days in the circulation. as the cell ages it becomes increasingly fragile and most RBC break down in the narrow vasculature of the spleen but some in the liver