Bleeding In Early Pregnancy, APHge, Medical Disorders And Fetology Flashcards
Mention CCC of vesicular mole
- Gestational hypertension
- Hyperthyroidism
- Trophoblastic embolization
- Hyperemesis gravidarum
- Theca lutein ovarian cyst
- Persistents GTN
- Infection
- Severe bleeding
- RDS dt 1,2,3
- DIC dt 1, 3, 7, 8
- Recurrence
Mention causes of pain in vesicular mole
- Distension leading to dull aching pain
- Colicky pain dt uterine contraction
- Sevre sharp pain dt uterine perforation (invasive mole), RTH theca lutein cyst, concealed hge
Describe the termination of pregnancy in case of VM
=Suction evacuation, blood should be available +/- misoprostol, 12 mm cannila for easy evacuation, oxytoxin helps E and dec B, suction is better guided by US
=Hysterectomy in toto in multiparous women no longer desiring fertility, MP wl severe infection or bleeding, invasive mole causing uterine perforation and intraperitoneal hge
Describe follow-up of VM by BHCG
New baseline 48 hrs after evacuatoin then
Weekly follow-up till undetectable for 3 successive wks (9-11 wks)
Monthly FU for 6m
Mention indications of prophylactic chemotherapy in VM
- Age >40 yrs
- BHCG >100,000 IU/L
- Theca lutein cyst >6 cm
- Significant uterine enlargement
- Unreliable to FU
Describe management of theca lutein cyst
Conservative as it disappears after evacuation by 2-4 months
Laparotomy only for complicated cyst (torsion rupture hge)
When is PV and VD allowed in PP?
- Mild APH
- Low lying placenta
- Under complete aseptic conditions
- Equiped hospital (OR)
- In labour
- Double set examination (for VD & CS)
Mention causes of cncealed accidental hge
- Intact placental margins
- Fetal membranes still attached to uterus
- Deeply engaged presnting part
- High rupture of membranes with intra-amniotic bleeding
Enumerate risk factors of PE
Personal: inc age, weight, nulliparity, FHx of PE
Obs: previous PE, molar pregnancy, hydrops fetalis, polyhydramnios, MFP (inc chorionic tissue and uterine overdistension)
Med: hypothyroidism, PGDM, APS, CKD
Mention CCC of PE (&E)
Maternal
1. Brain cerebral edema or hge
2. Retinal edema and hge
3. Pulomary edema
4. Cardiomegaly and hypertensive HF
5. Acute fatty liver, hepatic edema, subcapsular hge
6. Acute tubular and cortical necrosis
7.DIC,MAHA and HELLP
8. Placental abruption
Fetal: IUFD, IUGR, PTL, neonatal asphyxia
Remote: recurrence, ESRD, inc HTN, ISHD, VTE
Mention criteria of severity of PE
- BP >/= 160/110
- New onset of neurological symptoms e.g. cerebral or visual disturbance. Persistent headache
- Pulmonary edema
- Liver affection as indicated by s.transaminases > twice normal or persistent RUQ or epigastric pain not responding to medication
- sCr >1.1 mg/dlor doubling with no known cause
- Platelets <100,000/ ul
Describe dose and administartion of MgSO4
Loading dose: 4 g slow IV infusion over 15-20 min
IV regimen: 1-3 g/hr by IV drip
IM regimen (obsolete) 10 g with loading 5 g in each buttock then 5g/4-6 hrs slow IM
Continued for 24-48 hr after last fit or TOP
Mention the DD of fits during pregnancy
- Eclampsia
- Epilepsy
- Hysterical
- Cerebral strolke
- HTN encephalopathy
- CNS irritation
- Strychinine poisoning
Mention criteria of severity of eclampsia
Eden’s criteria:
1. Fits >10 times
2. Coma >6 hrs
3. Oliguria or anuria
4. Pulse >120/ min
5. Temp >/=39
6. SBP >200 mmHg
7. RR >/= 40/min
Mention risk factors for GDM
Personal: inc age, obesity, grandmultipara, FHx of DM
Obs: prev GDM, inc chorionic tissue (MFP), Hx of unexplained macrosomic baby, polyhydramnios, IUFD, perinatal loss, baby w/ CFMF, repeated abortion. Excessive gestational weight gain or glucosuria +2 on 2 occasions
Med: metabolic syndrome, PCO