Bits and Bobs

Question 1

Which drugs cause an exacerbation of gout? BANDA

Answer 1

beta-blockers
aspirin
niacin
diuretics 
ACE-inhibitor

Question 2

Which drugs decrease your folate levels?

Answer 2

methotrexate
anti-epileptics
trimethoprim

Question 3

Which drugs increase your blood glucose?

Answer 3

barbituate
thiazide diuretics
corticosteroids
birth control
niacin

Question 4

Cytochrome p450 inhibitors (slow down metabolism- longer in body)

Answer 4

Sodium valporate
Omeprazole
Fluoxetine- SSRI
Antibiotics

Anitfungals
Cranberry juice
Cimeitdine
Calcium Antagonist
Amiodarone

Question 5

Cytochrome p450 inducers (speed up metabolism- shorter in body)

Answer 5

Carbamezapine
Rifampicin
A
Phenytoin

Gliclazide
Barbituates
St Johns Wort

Question 6

Cytochrome P450 substrates

Answer 6

Clopidogrel
corticosteroids
Carbamezapine
OCP
Warfarin

Phenytoin
Amitryptaline
Theophylline
Sodium Valporate

Painkillers
Losartan
Omeprazole
Donepazil
Statins

Question 7

What are the nephrotoxic drugs?

Answer 7

Diuretics
Iodine
ACE- inhibitor
Metformin
Opioids
NSAIDs
Digoxin

Heparin
Aminoglycosides
Lithium

Question 8

First line abx for: eradication of h.pylori?

Answer 8

PPI with amoxicillin plus metronidazole

Question 9

First line abx for: acute pyelonephritis?

Answer 9

ciprofloxacin

2nd: co-amoxiclav

Question 10

First line abx for: PID?

Answer 10

ofloxacin bd plus metronidazole bd for 14 days

if high risk for gonorrhoea: ceftriaxone IM stat followed by doxycycline plus metronidazole

Question 11

First line abx for: acute otitis media?

Answer 11

none 1st line, consider delayed abx

2nd: amoxicillin

Question 12

First line abx for: pharyngitis/sore throat/ tonsillitis?

Answer 12

none 1st line

2nd line: phenoxymethylpenicillin

Question 13

First line abx for: CAP

Answer 13

CURB 65= 0 –> amoxicillin

CURB 65=1,2 & at home –> amoxcilin and clarithromycin/doxycycline

Question 14

First line abx for: exacerbation of COPD?

Answer 14

doxycycline stat then 5d of doxycycline/ clarithromycin/ amoxicillin

Question 15

First line abx for: UTI in pregnancy?

Answer 15

amoxicillin 
nitrofurantoin (avoid >36 weeks)
trimethoprim (avoid in first trimester)

Question 16

First line abx for: UTI

Answer 16

trimethoprin or nitrofurantoin

men: 7 days
women: 3 days

Question 17

First line abx for: cellulitis?

Answer 17

flucloxacillin qds 7-14 days

Question 18

First line abx for: impetigo?

Answer 18

flucloxacillin qds 7 days

Question 19

what is common first line antibiotic if penicillin allergic?

Answer 19

clarithromycin