Bipolar Disorder and Schizophrenia Flashcards

1
Q

what is bipolar disorder

A

brain disorder causing unusual shifts in mood, energy, activity levels and ability for day-day activities

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2
Q

what happens without treatment for bipolar & symptoms: (SHECASWS)

A
  • intense depression episodes
    -symptoms:
    Sadness
    Hopelessness
    Energy (lack)
    Concentration (lack)
    Anxiety
    Suicidal
    Weight
    Sleep (lack of sleep)
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3
Q

what happens when a person is manic:

A

-Feels supercharged, thinking they can do anything
-self-esteem soars out of control & cant sit still
-talk more, thoughts race & easily distracted
-reckless behaviour

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4
Q

what are signals of a manic episodes

A

when 3 or more manic symptoms happen everyday for a week + feelings of excitement

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5
Q

what is a manic or depressive mixed episode & where are they more common

A

When some with bp has depression and mania symptoms very close together or at same time = unpredictable behaviour
- more common is bp young people

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6
Q

what is psychosis

A

lost contact with reality caused by severe manic or depressive symptoms… hallucinations and delusions…. may lead to people with bp to be diagnosed with schizophrenia.

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7
Q

cause of bipolar

A

brain circuits in regulating mood, energy, thinking and biological rhythms function abnormally = mood and other changes

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8
Q

how does it affect daily life

A

-10-20 times more likely to commit suicide
-substance misuse

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9
Q

when does the first episode occur

A

often in mid 20s

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10
Q

what causes mania

A

functional excess of monoamine NT, e.g. dopamine, norepinephrine and serotonin.

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11
Q

what causes mania

A

functional excess of monoamine NT, e.g. dopamine, norepinephrine and serotonin.

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12
Q

what are 3 types of counselling:

A

1: cognitive behavioural therapy: for changing thoughts and behaviours that come with mood swings
2: interpersonal therapy: ease strain of bp of relationships
3: social rhythm therapy: help develop & maintain daily routines

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13
Q

what are the treatments of bp:

A

1st line: Atypical antipdychotic drugs e.g. olanzapine, rispridone, quetiapine and aripiprazole
2nd line: Li+ ion : which begin to work in 5 days but require several weeks
3rd line: antiepileptics e.g. valproic acid, carbamazepine…. require several weeks to work

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14
Q

what are non- pharmacological treatments for bp (social)

A

-Support groups:
- Depression and related affective disorder association (DRADA)
-Depression and bipolar support alliance (NDMDA)
-rehabilitation and habilitation

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15
Q

what are non- pharmacological treatments for bp (social)

A

-Support groups:
- Depression and related affective disorder association (DRADA)
-Depression and bipolar support alliance (NDMDA)
-rehabilitation and habilitation

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16
Q

Mechanism of action for Li+

A
17
Q

Lithium pharmacokinetics

A

-Given orally as carbonate salt
-enters cells cells through channels and ion-couples transporters for Na+
-excreted by glomerular filtration but Li+ is nephrotoxic

18
Q

Lithium drug interaction:

A