Bipolar Disorder Flashcards
1
Q
Risk of developing bipolar disease
A
you are more likely to get it if both or one of your parents has it then your sibling having it
2
Q
Genetic Heritability of Bipolar Disorder
A
80-90% have a family history
First degree relatives of people with bipolar disorder type 1 are 7 times more likely to develop BP
genetic concordance in identical twins is 33-90%
Adoption studies show it’s partly genetic
3
Q
Pathways
A
phospholipase c signaling cardiac b-adrenergic signaling glutamate receptor signaling corticotropin releasing hormone signaling endothelin 1 signaling cardiac hypertrophy signaling
