Bipolar Disorder Flashcards
Pathophysiology
Unknown. Thought to arise from a combination of genetics, physiological, environmental, & psychosocial factors.
Bipolar I
Consists of 1 or more manic or mixed episodes, & course of illness is usually accompanied by major depressive episodes.
Bipolar II
Consists of 1 or more major depressive episodes & accompanied by at least 1 hypomanic episode.
Risk Factors
- Family hx
- Drug abuse
- Periods of very high stress
- Major life-altering event
Are women & men at equal risk?
Yes. Women are more likely to experience rapid cycling & depressive symptoms.
Mania
Abnormal & persistently elevated, expansive, or irritable mood & increased energy (or activity) present for most of the time, nearly every day, or a week or more & accompanied by @ least 3 specific symptoms of mania.
Symptoms of mania?
- Inflated self-esteem or grandiosity
- Decreased need for sleep
- Talkative, pressured speech patterns
- Flight of ideas
- Distractability
- Increase in goal-directed activity
- Psychomotor agitation
- Excessive involvement in pleasurable activities that have a high potential for painful consequences
- Severe? –> Delusions, hallucinations
Hypomania
Not severe enough to markedly impair functioning or require hospitalization. Feels “on top of the world.”
Characteristics of manic episodes?
- Behavior excessive, overly enthusiastic
- Increased sexual behavior often seen
- Often follows a severe disappointment, embarrassment, or other psychic stressor
- Individual rarely believes they are sick.
Depressive episodes
Similar to depression. Many w/ bipolar disorder initially diagnosed w/ depression.
Rapid cycling (dysthymic)
4 mood episodes occuring within a year w/ periods of partial or full remission of 2 months or more or w/ immediate alternate periods of mania/hypomania & depression.
Mixed
Symptoms of both mania, depression present.
Cyclothymic disorder
Chronic, fluctuating mood disturbance involving numerous periods of hypomanic symptoms & numerous periods of depressive symptoms for at least 2 yrs.
- No severe symptoms (this would cause dx of manic disorder or MDD)
- Moody, unpredictable, temperamental
- Begins in adolescence, early adulthood
Pharmacologic Txs
- Lithium carbonate –> Rx of choice
- Anticonvulsants –> maintenance
- Atypical antipsychotics –> sedative & mood-stabilizing effects
What are initial episodes like in males?
Manic episodes