bipolar Flashcards

1
Q

this involves extreme mood swings between mania and episodes of depression

A

bipolar disorder

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2
Q

this means good mood, or the the state of being in a neutral mood

A

euthymia

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3
Q

this is characterized by elevated, expansive and irritable mood

A

mania

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4
Q

how many weeks should mania be present to be classified as bipolar disorder

A

at least 1 week

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5
Q

what are the signs and symptoms of mania

A

hyperactivity
elevated mood
distractibility
irritability, increased interest in sex, insomnia
grandiosity
flight of ideas
anger, anorexia
speech is rapid and loud, suicidal
talkative

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6
Q

this is mania but less severe

A

hypomania

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7
Q

must be present for at least 4 days to be considered bipolar disorder

A

hypomania

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8
Q

signs or symptoms of hypomania (at least 3)

A

grandiosity
decreased need for sleep
subjective sense that thoughts are racing
distractibility
increase in goal-directed activity
excessive involvement in fun but dangerous activities

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9
Q

this type of bipolar disorder has patient experience mania and depression

A

bipolar type 1

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10
Q

this type of bipolar disorder has patient experience hypomania and depression

A

bipolar type 2

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11
Q

this type of bipolar disorder has the patient experience non extremes of mania and depression

A

cyclothymia

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12
Q

how many times are first degree relatives of people with bipolar 1 more likely to develop bipolar 1 disorder than the general population

A

7 times

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13
Q

how many percent of chance does an offspring of someone with bipolar disorder have of developing another major psychiatric disorder

A

50%

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14
Q

how many percent is the concordance between bipolar 1 in identical twins

A

33-90%

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15
Q

what is the catecholamine hypothesis

A

An increase in epinephrine and norepinephrine
causes mania and a decrease in epinephrine and
norepinephrine causes depression

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16
Q

what is the psychodynamic etiology of bipolar disorder

A

Depression is the manifestation of losses. Therefore, the mania serves as a defense against the feelings of depression

17
Q

how does nature of wok cause bipolar disorder

A

Certain individuals have periods of high demands
followed by periods of few requirements

18
Q

what months are there significantly higher admission rates for patients with bipolar disorder

A

may, june, and july

19
Q

what is the first line treatment for bipolar disorder

A

lithium (eskalith)

20
Q

what class is lithium (eskalith)

A

antimanic agent

21
Q

what is the lag period for lithium (eskalith)

A

5 to 14 days

22
Q

why is lithium contraindicated for pregnant patients

A

it crosses blood brain barrier and placenta, and is distributed in sweat and breast milk

23
Q

what are the indications for lithium

A

bipolar disorder that is unresponsive to lithium
patients that cant tolerate side effects
patients with conditions contraindicated like pregnancy

24
Q

these anticonvulsants are known to increase levels of GABA

A

valproic acid and topiramate

25
Q

these anticonvulsants are known to inhibit the kindling process

A

valproic acid and carbamezapine

26
Q

what are anticonvulsants used as mood stabilizers

A
  • carbamezapine (tergetol)
  • divalproex (depakote)
  • gabapentine (neurontin)
  • lamotrigine (lamictal)
  • topiramate (topamax)
  • oxcarbazepine (trileptal)