biostats

Question 1

Receiver operating characteristic curve

Answer 1

area under the curve = diagnostic accuracy. As AUC inc, accuracy inc

Question 2

A stratified analysis will help to uncover ____

Answer 2

effect modification

Question 3

Hawthorne effect

Answer 3

behavior changes from awareness of being observed

Question 4

External validity

Answer 4

how generalizable are the results of a study to other populations?

Question 5

Sensitivity analysis

Answer 5

repeat primary analysis after modifying certain criteria to see if modifications affect initial results

Question 6

Net clinical benefit

Answer 6

= possible benefit - possible harm

Question 7

Intention to treat analysis

Answer 7

participants in trial should be analyzed in group they were randomized in, regardless if they dropped out or didn’t adhere to the regimen

Question 8

intention to treat analysis preserves ____

Answer 8

randomization

Question 9

Standardized mortality ratio

Answer 9

= #observed deaths/#expected deaths

Question 10

95% of observations/population lie within _____ standard deviations of the mean

Answer 10

2

Question 11

Attributable risk %

Answer 11

= (risk exposed - risk unexposed) / risk exposed

Question 12

Relative Risk

Answer 12

A/(A+B) / C/(C+D) = prob dz in +exp/ prob dz in -exp

Question 13

Odds ratio

Answer 13

AD/BC = odd exp in +dz/ odd exp in -dz