Biopsychology Flashcards

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1
Q

Circadian rhythms AO1

A

24 hour cycles that happen once in a day including physical, mental and behavioural changes. Reset by the levels of light.

Sleep wake cycle is an example of a circadian rhythm. It dictates when animals and humans should be asleep and awake. Daylight(exogenous zeitgeber) makes us feel awake during the day and drowsy during the night. Light is detected by the eyes which then send a message concerning the level of brightness to the SCN.

Core body temperature is another example of a Circadian rhythm. Lowest during the day at 36 degrees during 4am and highest during the evening at 38 degrees during 6pm. Sleep occurs when core temperature starts to drop and body temperate rises towards end of sleep cycle encouraging alertness in the morning.

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2
Q

Circadian rhythms AO3

A

Supporting research: siffre(1975) found after staying underground with no light or clocks for a while that his 24 hour sleep wake cycle was increased due to a lost perception of time due to absence of external cues which altered his circadian Rythm. Believe the date to be a month earlier.

Aschoff and Wever found after convincing participants to stay in an underground bunker for 4 weeks deprived off natural light, that all but one participant displayed a circadian rhythm between 24 and 25 hours. Both siffre and this study suggest natural sleep cycle may be slightly longer than 24 hours.

Practical application to shift work:
Knowledge or circadian rhythms has given researchers a better understanding of the consequences that occur as a result of their disruption. E.g. night workers engaged in shift work experience reduced concentration at around 6 in the morning meaning mistakes and accidents are more likely(boivin et al 1966)

Practical application to drug treatment:
Research into circadian rhythms has revealed that there are certain peak times during the day or night when drugs are likely to be at their most effective. Lead to development of guidelines to do with timing of drug doses for a whole range of medication(baraldo 2008)

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3
Q

Michael siffre cave study

A

Research done to investigate circadian rhythms and effect of external cues like light on the systems. Siffre found that absence of external cues significantly altered his circadian rhythm. After staying underground with no light or clocks he lost perception of time by believing it was a month earlier than it was when he had come out. He believed it was august when it was September. Suggests his 24 hour sleep wake cycle was increased by the lack of external cues. Making him believe one day was longer than it was.

AO3
.Study produced a lot of quantitative and qualitative data.
.study was done over a long time allowing siffre to investigate his sleep wake cycle and show how irregular it became.

.only one participant so hard to generalise findings.
.internal validity affected as lights turned on to wake him up and turned off to allow him to sleep could have acted as an external cue.

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4
Q

Infradian rhythms AO1

A

An example is
Menstrual cycle: governed by hormones roughly on a 28 day basis. Oestrogen levels rise to release an egg from the ovary and progesterone helps the womb lining to grow. If there is no pregnancy then the womb lining sheds.

Seasonal affective disorder: type of depressive disorder which is seasonal. Described as a mental disorder in DSM-5. When there are reduced daylight hours in the winter it can trigger a low mood in the sufferers(circannual rhythm) lack of light causes increased melatonin levels and which creates the low mood. Can also be classed as a circadian rhythm as it’s experience can be due to the disruption of the sleep wake cycle and this can be attributed to prolonged periods of daily darkness during winter.

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5
Q

Infradian rhythms AO3

A

Penton-volk 1999 study suggests women prefer feminised faces of men in their least fertile stage and more masculine faces in their most fertile stage.

Real word application: sanassi found that a light box can be used to reset melatonin levels and relieve symptoms in up to 80 percent of SAD patients.

Stern and McClintock found that women could synchronise their periods by being exposed to other women’s pheromones. This suggests we should take into account external factors of infradian rhythms.

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6
Q

Ultradian rhythm AO1

A

More than one cycle in 24 hours(happens more than once in 24 hours)

This cycle alternates between REM (rapid eye movement) and NREM (non-rapid movement) sleep and consists of five stages.

An example of an ultradian rhythm is the sleep cycle:
It has 5 stages which can be identified using an EEG, showing the electrical activity of the brain.

Stage1 and 2: light sleep where you can be easily woken. In stage 1 alpha waves are produced and in stage 2 alpha waves continue but with sleep spindles. (Occasional random changes)

Stages 3 and 4: deep sleep or lower wave sleep. Brain produces lower delta waves Which have a lower frequency and higher amplitude. Difficult to wake someone up in these stages.

Stage 5: REM(rapid eye movement) sleep. The body is paralysed and the activity of the brain resembles someone who is awake. It produces theta waves and the eyes sometimes move around. This is when dreams are most likely to occur.

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7
Q

Ultradian Rythm AO3

A

Although the method of using EEG to record sleep brain wave activity, it can be invasive and disturb the sleep of participants reducing ecological validity.

Researchers now have an improved understanding of how older people have less slow wave sleep allowing for recommendations of medication and relaxation techniques.

However there are individual difference in each participants stage duration. Tucker et al. Has found large differences between the duration of each stage for different people. Meaning this study cannot be generalised.

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8
Q

Effect of endogenous pacemakers on sleep wake cycle

A

They are internal mechanisms which determine the biological rhythms for the body e.g. circadian rhythms.
Sometimes referred to as the internal biological clock but can be affected by external environment e.g. light.

SCN is a major factor in sleep wake cycle and is the most important type of endogenous pacemaker.
Specific biological triggers are involved with someone falling asleep:

-eye detects low levels of light.
-then sends this information to SCN
-SCN the. Alerts pineal gland to secrete melatonin.
-melatonin increases which induces sleep.

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9
Q

Effect of endogenous pacemakers AO3

A

Siffre 1973 cave study demonstrating that humans fall into roughly a 24 hour sleep wake cycle, suggests evidence through its findings that an internal biological clock determines the sleep wake cycle. Supports the effects of endogenous pacemakers.

Reductionist as peripheral oscillators found in other organs have their own Circadian Rhythms suggesting the influence on the sleep wake cycle is more complex than previously thought.

Chipmunk study by decoursey et al suggest through findings that SCN is important. SCN was destroyed in 30 chipmunks and they were returned to the wild. When they returned most were killed by predators not long after as they left nests wrong time of the day.

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10
Q

Effect of exogenous zeitgebers

A

They are any factors in the sleep wake cycle which act as external cues to either wakefulness or sleepiness. E.g. light and social cues.

.Light can be detected by the eyes but also by the skin influencing secretion of hormones and blood circulation.

.social cues such as mealtime, bedtime, and work schedule can be used to compensate for the lack of light, using these cues instead. They also train babies circadian rhythm to match 24 hours.

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11
Q

Effect of exogenous zeitgebers AO3

A

Real world application:
Knowledge of E.Z. Can help decrease the impact jet lag has on our sleep wake cycle by providing light and meals at certain times on a plane to match the destinations time zone.

Campbell and Murphy (1988)
Demonstrated that light(Torch) is a key exogenous zeitgeber even when shone on the back of participants knee as it disrupted their sleep cycles by up to 3 hours.

Siffre believed it to be a month earlier than it was when he emerged. Suggest his cycle was increased by the lack of external cues.

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12
Q

Consequence of disruption to biological rhythms

A

Biological rhythms are regulated by two factors E.Z. And E.P.
E.P. Are internal mechanisms determining biological rhythms of the body.
E.Z. Are any factors in the sleep wake cycle which act as external cues to either wakefulness or sleepiness.

Disturbance/ lack of these factors can result in many consequences for instance:

.shift work related issues where night shift workers experience low concentration around 6 in the morning which can result in accidents and also poor health problems. Happens due to disruption in circadian rhythm and the stress of adjusting to different sleep/wake patterns as well as lack of quality sleep during the day. Shift workers 3 times more likely to develop heart disease.

.jet lag happens due to a disturbance in the exogenous zeitgebers as the patterns of light and social cues such as meal times change.

.Disturbance of SCN(endogenous pacemaker) can result in problems as showcased by decoursey who destroyed the SCN connections in 30 chipmunks and returned them to the wild. Many were killed by predators straight away as they had left their nest at the wrong time of the day.

.siffre case study suggests through results that a lack of exogenous zeitgebers such as daylight caused his biorhythm to settle around 25 hours and cause him to lose perception of time causing him to think it was a month earlier than it was when he emerged.

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13
Q

Consequences of disruption to biological rhythms AO3

A

Animal studies such as the chipmunk study are unethical as animals cannot give consent to have their SCN removed. The studies are also not generalisable to humans as they are done on animals.

Knowledge of exogenous zeitgebers can help decrease the impact jet lag has on our sleep wake cycle by providing light and meals at certain times on a plane to match the destination time zone.

Shift work related issues can be resolved by keeping workers on their schedule that are based on their sleep wake cycle.

Studies such as siffre which showcase the consequence of disruption to the circadian rhythm can not be generalised as the study was only on siffre himself and people have individual differences.

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14
Q

Plasticity

A

Brain’s tendency to change and adapt(functionally and physically)
As a result of experience and new learning. Between 2 and 3 years old we have twice as many neural connections as we do as an adult. The synaptic pruning strengthens the connections we use and deletes those we don’t. Our brains are plastic throughout our lives.

Maguire et al study showed this in taxi drivers who had increased grey matter in posterior hippocampus.

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15
Q

Plasticity AO3

A

Maguire et al study showed a positive correlation in the time spent on the job for london taxi drivers and the amount of grey matter they had. Suggesting brain had changed as a result of the learning taking place.

Draganski et al examined brains of medical students three months before and after final exams there were changes in the posterior hippocampus and parietal cortex.

Support studies such as maguire has good design with the use of a control group allowing us to say there is a significant difference between taxi drivers and other non taxi drivers.

Tang et al. Found that 4 weeks of meditation increases white matter in the anterior cingulate cortex. Which is responsible for self control and regulation.

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16
Q

Maguire et al

A

Used london taxi drivers as participants who had taken the knowledge test.
Used MRI scans and found there was increased grey matter in the posterior hippocampus in comparison to a control group.
This area is associated with spatial and navigation skills.
The longer they had been on the job the more grey matter they had.
Suggest that the brain has changed as a result of the learning taking place.

17
Q

Functional recovery

A

After an injury or trauma the brain uses unaffected areas to compensate and adapt for the damaged areas.
Therefore functional recovery is a form of plasticity.
Initially this will happen very quickly but will slow down over the several weeks/months after which therapy is useful.
Recovery is more likely the younger you are.

How does it work?
-Axon sprouting: new nerve endings grow and connect with undamaged areas to create new pathways
-recruitment of homologous(similar) areas: the same areas on the opposite side(hemisphere) of the brain take over e.g. Broca’s area.
-reformation of blood vessels.
-neuronal unmasking: dormant synapses open connections near damaged areas.

18
Q

Functional recovery AO3

A

Supporting research:
Taijuri et al found that if rats had their brains injected with stem cells at the site of trauma then new neuron like cells migrated to the injury site.

Real world application:
This has led to the development of neurorehabilitation which uses movement therapy with stroke patients.

Age:
Ebart et al found that neural regeneration is less effective in older brains. Therefore, individual differences need to be considered when assessing recovery.

19
Q

Nervous system

A

Consists of the CNS and Peripheral nervous system.
.CNS consists of the spinal cord and brain. The brain has two hemispheres the outer layer is called the cerebral cortex. Spinal cord is responsible for reflexes.
.PSN sends messages to and from the CNS via neurons. It’s broken down into the somatic and autonomic nervous system.
.somatic nervous system is responsible for voluntary movements and transmits information from the senses to the CNS and directs muscles to act.
.autonomic nervous system is responsible for involuntary tasks such as breathing, digestion and is broken down into parasympathetic and sympathetic nervous systems.
.they are both involved in fight or flight with parasympathetic returning the body back to rest state.

20
Q

Neurons

A

Cell body contains nucleus(chromosomes) from the cell body. Dendrites extend from the cell body and collect electrical impulses from other neuron’s towards the cell body. The axon carries impulses away from the cell body and they’re covered by a fatty layer called the myelin sheath which increases the speed of transmission. The breaks in the myelin sheath called nodes of ranvier force the impulses across the gaps speeding up the transmission.

Motor neurone: carry signals from CNS to effectors(muscles/glands)

Relay neuron: connect sensory neuron to motor neurons or other relay neurons.

Sensory neuron: carry signals from receptors to CNS

21
Q

Synaptic transmission

A

Gap between neurons is called the synapse. Chemicals that diffuse across these gaps are called neurotransmitters.

Electrical impulses called the action potential travel along the axon of the transmitting neurons dendrites.

This triggers the nerve ending of the presynaptic neuron to release neurotransmitters from synaptic vesicle.

These chemicals diffuse across the synapse and bind with the receptor sites on the membrane of the post synaptic neurone.

This stimulates the post synaptic neuron to transmit electrical impulses.

Reuptake: some of the neurotransmitter gets reabsorbed back into the pre synaptic neuron or gets broken down by enzymes.

22
Q

Summation

A

Overall net combined effect of inhibitory and excitatory neurotransmitters

Excitatory is
Neuron becoming more positive due to depolarisation more Na+ ions going in and therefore neurone more likely to fire a impulse

Inhibitory is
Neurone becoming more negative due to hyperpolarisation more K+ ions entering and therefore neurone is less likely to fire an impulse

A threshold has to be reached in order for the action potential to be generated too

23
Q

Endocrine system

A

Consists of glands that secrete hormones into the blood stream to control vital functions of the body.
Pituitary gland controls the release of hormones from all the other endocrine glands.

Pituitary gland:
Master gland that controls other glands aswell. Releases ACTH during the stress response and oxytocin during childbirth.

Hypothalamus:
Stimulates and activates the pituitary gland

Pineal Gland: releases melatonin to control biorhythms such as sleep wake cycle.

Thyroid gland:
Releases thyroxine to control metabolism.

Adrenal gland:
Adrenal medulla releases adrenaline/noradrenaline in fight or flight. Adrenal cortex releases cortisol in chronic stress response.

Ovaries:
Regulates the menstrual cycle and pregnancy by releasing oestrogen.

Testes:
Produces testosterone for male sex characteristics and muscle growth.

24
Q

Fight or flight AO1

A

Fight or flight response enables us to react quickly to stressful or threatening situations.
Endocrine and autonomic systems work together during the fight or flight.

Stressor picked up in the environment.
The amygdala then sends stress signals to the hypothalamus.

Hypothalamus then activates the pituitary gland which triggers the sympathetic nervous system
(dilated pupils, sweating, increased heart rate, increased breathing rate, inhibited digestion, inhibited saliva production)

The SNS then activates the adrenal medulla
Adrenal medulla then released adrenaline/noradrenaline.

This then prepares the body for fight or flight.

After a while the parasympathetic branch activates bringing the body back to normal.

25
Q

Fight or flight AO3

A

Taylor et al. Did research and found that women in stressful situations protect themselves by caring and nurturing for their young(tending) or by forming alliances with others(befriending)

Lee and Harley research showed that SRY gene found in male Y chromosome is what is responsible for fight or flight in males. SRY gene is absent in females.

Overall FFR lacks ecological validity and has gender bias as it only applies to males. Study was only conducted on men.

26
Q

Localisation of function

A

Motor centre:
Controls voluntary actions on the opposite side of the body(left hemisphere controls right side of the body)

Somatosensory centre:
Sensory information from the skin is processed here.

Visual centre:
Receives visual information from each eye.

Auditory centre:
Processes speech based information

Borcas area: mostly found in left hemisphere and is responsible for speech production. Damage causes brocas aphasia which is struggling to speak fluently.

Wernickes area:
Left hemisphere mostly, damage will result in wernickes aphasia- patients will be able to speak but words will lack meaning.

Brocas aphasia: speech lacks fluency
Wernickes aphasia: speech lacks meaning

27
Q

Localisation of function AO3

A

Brain scans:
Peterson et al. Used brain scans to show how wernickes area was active during a listening task and brocas was active during a reading task. Proving the areas have different functions.

Holistic?
Not all research agrees that cognitive functions are localised in the brain. E.g. FMRI scans show that language functions may be distributed across the cortex rather than just Broca’s area and wernickes area.

Lashley found that by removing different areas of the cortex in rats learning a route through a maze that there was no difference in their ability to learn after surgery. Suggest processes such as learning are not localised but processes more holistically.

28
Q

Hemispheric lateralisation

A

Language is lateralised as the Brocas and wernickes area is predominantly found in the left hemisphere. Many other functions are not lateralised as they are found across the hemisphere e.g. motor centre.
The brain is cross wired as the left hemisphere controls the right side of the body and vice versa e.g. visual processing or movement.

29
Q

Split brain research

A

Sperry research

11 participants who had an operation to cut corpus callosum due to epilepsy were studied alongside a control group of non epilepsies.
Using a split visual field, images were presented to either the left visual field or the right visual field.
If it was shown to the right visual field then participants could describe what they saw but not if it was shown to the left visual field.
This is because the right hemisphere cannot process language and could not communicate with the left hemisphere which is responsible for processing language.
However if they were asked to select a matching object with their left hand even if they could not describe it they would guess it right.

30
Q

AO3

A

Individual differences:
Some of the Brains of participants were more disconnected than others and some had been on drug therapy longer than others.

Oversimplified:
Split brain research has caused the oversimplification of the functional differences between hemispheres. Plasticity shows us that the other hemisphere can perform the same function when required to do so I.e. functional recovery.

Validity:
The set up of the study was artificial and lacked ecological validity. This is because in real life, using both eyes would compensate for a severed corpus callosum and so these studies don’t represent how the brain would work in reality.

Generalisability:
The control groups did not have a history of epilepsy and so it was not a valid comparison. The split brain patients also have very different Brains to people without epilepsy and so results are not generalise-able to a wider population