Biopsy Flashcards
Loculated fluid in or under the epithelium of skin or mucosa
Bulla
Superficial ulcer (excoriation)
Erosion
Circumscribed area of color change without elevation
Macule
Small palpable mass, elevated above the epithelial surface
Papule
Large palpable mass, elevated above the epithelial surface
Nodule
Flat elevated lesion; the confluence of papules
Plaque
Cloudy or white vesicle (PMN Leukocytes)
Pustules
Macroscopic accumulation of keratin; AKA leukoplakia
Scale
Loss of epithelium
Ulcer
Small loculation of fluid in or under the epithelium
Vesicle
Feel of the pulse (of a lesion)
Thrill
Sound the pulse makes (in a lesion)
Bruit
Levels of what specifics are investigated when a biopsy is sent to the laboratory?
Calcium Phosphorus Alkaline Phosphatase Serum Proteins Others
After observation or nonsurgical therapy for 10-14 days you see no signs of improvement in a lesion. What is the next step?
Decision to biopsy & Determining the difficulty of the biopsy procedure
What is the main indication for a biopsy
More than two weeks with no apparent etiologic basis; Inflammatory lesions that do not respond to local tx in 10-14 days
Lesions that raise suspicion of malignancy
- Erythroplasia
- Ulceration
- Duration
- Growth rate
- Bleeding
- Induration
- Fixation
Which type of biopsy is indicated for large areas of mucosal change and is done by scraping a few cells from that area?
Cytology biopsy
-Smear & fixate over glass slide
Which type of biopsy is indicated when a lesion is expected to contain fluid and/or believed to be an intraosseous lesion
Aspiration
Which type of biopsy is indicated for an extensive lesion (>1 cm), is in a hazardous location or has high malignancy suspicion; which is done by taking a piece of the lesion?
Incisional
- A sharp scalpel is used…avoid electrosurgery and cautery (would ruin margins of the samples)
- Cut has a “V” shape
How are incisional biopsies cut
Wedge Fashion (Deep & Narrow)
Which type of biopsy consists of removing the entire lesion and is indicated for small lesions (
Excisional
What are biopsy specimen stored in after removal?
10% fomalin solution (4% formaldehyde)—20x the volume of the specimen (total immersion)
What type of biopsy is done on an intraosseous lesion that shows radiolucent on x-ray?
Aspiration
If bone is to be removed for sampling of an intraosseous lesion, what surgical technique should be performed and how much bone should be removed for biopsy?
Mucoperiosteal flap; 4-5mm of sound bone around the lesion
What are the names of the 2 burs used to create an osseous window when removing bone for biopsy within an intraosseous lesion?
Round, Trephine
