Biopsy

Question 1

Loculated fluid in or under the epithelium of skin or mucosa

Answer 1

Bulla

Question 2

Superficial ulcer (excoriation)

Answer 2

Erosion

Question 3

Circumscribed area of color change without elevation

Answer 3

Macule

Question 4

Small palpable mass, elevated above the epithelial surface

Answer 4

Papule

Question 5

Large palpable mass, elevated above the epithelial surface

Answer 5

Nodule

Question 6

Flat elevated lesion; the confluence of papules

Answer 6

Plaque

Question 7

Cloudy or white vesicle (PMN Leukocytes)

Answer 7

Pustules

Question 8

Macroscopic accumulation of keratin; AKA leukoplakia

Answer 8

Scale

Question 9

Loss of epithelium

Answer 9

Ulcer

Question 10

Small loculation of fluid in or under the epithelium

Answer 10

Vesicle

Question 11

Feel of the pulse (of a lesion)

Answer 11

Thrill

Question 12

Sound the pulse makes (in a lesion)

Answer 12

Bruit

Question 13

Levels of what specifics are investigated when a biopsy is sent to the laboratory?

Answer 13

Calcium
Phosphorus
Alkaline Phosphatase
Serum Proteins
Others

Question 14

After observation or nonsurgical therapy for 10-14 days you see no signs of improvement in a lesion. What is the next step?

Answer 14

Decision to biopsy & Determining the difficulty of the biopsy procedure

Question 15

What is the main indication for a biopsy

Answer 15

More than two weeks with no apparent etiologic basis; Inflammatory lesions that do not respond to local tx in 10-14 days

Question 16

Lesions that raise suspicion of malignancy

Answer 16

• Erythroplasia
• Ulceration
• Duration
• Growth rate
• Bleeding
• Induration
• Fixation

Question 17

Which type of biopsy is indicated for large areas of mucosal change and is done by scraping a few cells from that area?

Answer 17

Cytology biopsy

-Smear & fixate over glass slide

Question 18

Which type of biopsy is indicated when a lesion is expected to contain fluid and/or believed to be an intraosseous lesion

Answer 18

Aspiration

Question 19

Which type of biopsy is indicated for an extensive lesion (>1 cm), is in a hazardous location or has high malignancy suspicion; which is done by taking a piece of the lesion?

Answer 19

Incisional

• A sharp scalpel is used…avoid electrosurgery and cautery (would ruin margins of the samples)
• Cut has a “V” shape

Question 20

How are incisional biopsies cut

Answer 20

Wedge Fashion (Deep & Narrow)

Question 21

Which type of biopsy consists of removing the entire lesion and is indicated for small lesions (

Answer 21

Excisional

Question 22

What are biopsy specimen stored in after removal?

Answer 22

10% fomalin solution (4% formaldehyde)—20x the volume of the specimen (total immersion)

Question 23

What type of biopsy is done on an intraosseous lesion that shows radiolucent on x-ray?

Answer 23

Aspiration

Question 24

If bone is to be removed for sampling of an intraosseous lesion, what surgical technique should be performed and how much bone should be removed for biopsy?

Answer 24

Mucoperiosteal flap; 4-5mm of sound bone around the lesion

Question 25

What are the names of the 2 burs used to create an osseous window when removing bone for biopsy within an intraosseous lesion?

Answer 25

Round, Trephine