Biopsy

Question 1

Minimal change disease

Answer 1

Light - normal
Electron - fusion of podocytes and effacement of foot processes

Question 2

Focal segmental glomerulosclerosis

Answer 2

Light - focal and segmental sclerosis and hyalinosis
Electron - effacement of foot processes

Question 3

Membranous glomerulonephritis

Answer 3

Spike and dome
Thickened basement membrane with sub epithelial electron dense deposits

Question 4

Post strep glomerulonephritis

Answer 4

Electron - sub epithelial humps
Immunofluoresence - starry sky

Question 5

Membranoproliferative glomerulonephritis type 1

Answer 5

Tram trak
Subendothelial and mesangial immune deposits

Question 6

Membranoproliferative glomerulonephritis type 2

Answer 6

intramembranous immune complex deposition with dense deposits

Question 7

Alport’s

Answer 7

Basket weave
Longitudinal splitting of lamina sense of glomerular basement membrane

Question 8

Good pasture’s

Answer 8

Linear IgG deposits along glomerular basement membrane

Question 9

Granulomatosis with polyangitis

Answer 9

Epithelial crescent in Bowman’s capsule

Question 10

Diffuse proliferative glomerulonephritis

Answer 10

Wire loop
Endothelial and mesangial proliferation, thickened capillary wall
Electron - sub endothelial immune deposits

Question 11

IgA nephropathy

Answer 11

Mesangial hypercellularlity
Immunofluoresence - IgA and C3

Question 12

Spike and dome

Answer 12

Membranous glomerulonephritis

Question 13

Starry sky

Answer 13

Post strep glomerulonephritis

Question 14

Trans trak

Answer 14

Membranoproliferative glomerulonephritis type 1

Question 15

Basekt weave

Answer 15

Alport’s

Question 16

Wire loop

Answer 16

Diffuse proliferative glomerulonephritis