Biopharmaceutics Flashcards

1
Q

What are the two ways of drug delivery across the mucus layer

A

Mucoadhesive- drug adheres to mucus and carried along GIT

Mucopenatrant- Drug penetrates thru mucus to get to epithelium (have to use PEG again)

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1
Q

What are the 5 methods of drug absorption

A

Transcellular (passive)
Paracellular (tight junctions)
Transcellular (active transport)
Micelles (lipid abs)

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2
Q

What is GALT absorption

A

Endocytosis via M cells in Peyers patch in SI

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