Biopharmaceutics Flashcards
1
Q
What are the two ways of drug delivery across the mucus layer
A
Mucoadhesive- drug adheres to mucus and carried along GIT
Mucopenatrant- Drug penetrates thru mucus to get to epithelium (have to use PEG again)
1
Q
What are the 5 methods of drug absorption
A
Transcellular (passive)
Paracellular (tight junctions)
Transcellular (active transport)
Micelles (lipid abs)
2
Q
What is GALT absorption
A
Endocytosis via M cells in Peyers patch in SI