Biomed R Elememdorf

Question 1

Glut-4 is mediated through which other molecule besides glucose?

Answer 1

Insulin

Question 2

Secondary Active Transport is what

Answer 2

Transport across a membrane that is dependent upon concentration gradients and not energy directly.

Question 3

How does Ubuain and digitalis work?

Answer 3

Inhibits sodium potassium pumps and thus calcium is not getting exported so the hearts contraction is stronger.

Question 4

AE1 has a sidekick enzyme, what is it?

Answer 4

Carbonic anhydrase

Question 5

AE1 is important in which processes?

Answer 5

Stomach acidification/ born reabsorption

Question 6

which Gluts are involved in nutrient absorption?

Answer 6

Glut 2 and Glut 5

Question 7

Glut 2 is found where? What’s its km?

Answer 7

Pancreas, Liver, Small Intestine, Kidney
Km of 15 (Really low so it’s the worst affinity to binding to glucose)

Question 8

Glut 1 is found? What’s its Km?

Answer 8

Erythrocytes, Brain, Placenta, Kidney, Colon
Km= 1.5

Question 9

Glut 5 is found? What’s its km?

Answer 9

Glut 5 is found in small intestine and muscle.
Km of -

Question 10

Glut 4 is found where? What’s special about it? What is its km?

Answer 10

Muscle and fat
It can be activated via insulin
Km = 1.5

Question 11

Glut 3 is found? What is its km?

Answer 11

Brain, Placenta, Kidneys

Question 12

Integrins are important for…

Answer 12

Inducing cellular pathways
Stabilizing the cell through the binding to a hemidesmosomal plaque.

Question 13

What are the two transporters with hemophiliac interactions?

Answer 13

Cadhesion
Ig superfamily

Question 14

What is the difference between a symporter and anti porter

Answer 14

Symporter transmits things across the membrane in the same direction
Antiporters transport things across membranes in opposite directions.

Question 15

What are examples of heterophilic interactions?

Answer 15

Integrins
Selectins