Biomaterials Flashcards

1
Q

What are the roles of water

A
  1. Solvent- in sugar, amino acid etc. all polar
  2. Temp buffer-high specific heat capacity
  3. Metabolite-collection of reactions in cells (metabolism). Water is reactant.
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2
Q

How much % of body made of water

A

65%

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3
Q

What influences reactions in body

A
  1. Enzymes- catalyse reactions & are molecules with temp optimum & pH (7.4)
  2. Salt conc
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4
Q

Extremeophiles

A

Extremophiles are organisms that survive in extreme conditions, like high heat, cold, salinity, or acidity. Examples include thermophiles (heat-loving) and halophiles (salt-loving).

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5
Q

pH equation & Kw

A

pH=-log[H³O+]
Where [H³O+]= 1M to 10^-14
Ke=[H+][OH-]
Where pH+pOH=14

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6
Q

Deadly pH value

A

<6.8 or 7.8>

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7
Q

What’s an acid

A

Proton donor. Must contain H in formula

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8
Q

What’s a base

A

Proton acceptor. Must contain a lone pair of e- to bind with H+

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9
Q

Acid + Base—> Conjugate acid + Conjugate base. What is Ka

A

Ka= ([C acid][C base]. )/ [HA]

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10
Q

Name some strong acids

A

HClO3 HCLO4….post H+ halogen combos

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11
Q

Name some strong base

A

Group 1 metals with OH (grp2??)

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12
Q

Weak base & acid eg

A

HF, HCN, H2S-acid
HS-, C5H5N-base

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13
Q

Equation of pH of a weak acid (don’t need for exams)

A

PH= pka +log([A-][HA])
(Ca-x)—>x + x
Where x= [H]
[H]²+Ka[H]- KaCa=0
(Henderson-Hasselbalch equation)

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14
Q

Buffer

A

Le chatelier

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15
Q

Homeostasis

A

Property of a system in which variables are regulated so that internal conditions remain stable & relatively constant

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16
Q

Buffer solution eg

A

Blood

17
Q

Acidosis & Alkilosis

A

.
Aci- pH<7.35, kidney fail to excrete enough acid, diarrhoea (HCO3- lost), hypoventilation (too less CO2)
.
Alki-pH>7.45 vomiting & hyperventilation (too much CO2)

18
Q

What’s lactic acid

A

End product of anaerobic oxidation of glucose, induces muscle pain.

19
Q

Poly lactic acid

A

Used in implants & breaks down into lactic acid as pH decreases

20
Q

Use of buffer in cell culture

A

Q. Balance salt soon
2. PBS Sol.